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Coming soon

More insight about each category is detailed below:

  1. Create new modalities and encourage paradigm shifts.

    1. Creation of versatile modalities such as protein medicines, antibody drugs, nucleic acid medicines, cell and regenerative medicine, and gene therapy
    2. Creation of novel new modalities that encourage a paradigm shift in specific disease areas, such as adjuvant vector cell (aAVC) technology
    3. Creation of pathophysiological specific modality technologies such as cell regeneration
  2. Find new drug discovery targets and answer unmet needs.

    1. Focus on diseases that unmet needs are clear.
      Priority will be given to diseases that can make use of the strengths of RIKEN drug discovery, such as rare diseases, infectious diseases, CNS diseases, immune diseases, etc.
    2. It is positioned as a medium- to long-term theme centering on infectious disease, especially viral diseases.
      We will make use of the experience of the new Corona Special Project, which we challenged by making full use of RIKEN's modalities such as small molecule medicines, antibody drugs, and aAVC technology.
    3. We will build a pipeline using new modalities that are created by RIKEN, such as aAVC technology, and promote a paradigm shift in specific disease areas.
  3. Explore the direction of "target × modality" evolution.

    In the past, the evolution of modality has been a major driving force in creating the evolution of drug discovery. We will challenge this approach to promote the evolution of "target × modality" by making full use of riken's advanced technology related to life sciences. Specifically, we will start with the following items and gradually challenge the direction of new evolution.

    1. Conversion of protein and antibody drugs to small molecules
      A small percentage of cytokine signals have been shown to be substituted with small molecules, and this fact finds universal law and aims for the next generation of drug discovery.

RIKEN is full of science and technology that produces two elements of "target" and "modality", and I am confident that if we release this power toward drug discovery with our own point of focus, we can realize further evolution of drug discovery on our own.

Program Overview

Program Overview
name RIKEN TRIP Headquarters
Program for Drug Discovery and Medical Technology Platforms
inauguration April 1, 2010
Program Director KUREBAYASHI Yoichi
purpose We will promote seeds related to "target × modality" born from basic research as a theme or project for drug discovery and medical technology in order to optimize drug discovery processes in pharmaceutical companies and technologies that are actually utilized in the medical field. Specifically, we aim to discover excellent seeds cultivated in basic research, optimize them using drug discovery infrastructure units and external networks installed at RIKEN centers, etc., and ultimately alliance with companies and medical institutions.

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