Bussiness DevelopmentAlliance, cooperation, and coordination of themes and projects – Collaboration with RIKEN Innovation

The final objective of this program is to transfer the advancement of drug discovery and medical technologies to companies or medical institutions. We are exploring the exceptional seeds of drug discovery and medical technology nurtured in basic research at RIKEN or collaborating universities and research institutes. We are conducting seed identification and lead optimization utilizing drug discovery platforms at RIKEN and other external platform networks. We will select candidate compounds or antibodies for development and prepare for clinical development. We also provide support for the clinical development of cell therapy and regenerative medicine projects.

We support forming an alliance of themes and projects on collaborative research or initiating licensing with companies or medical institutions.

Fig.1 Alliance, Cooperation, Coordination

We are seeking partners for drug discovery and medical technology themes and projects at all stages of research and development. The business development office handles alliances for collaboration with companies, universities, and external research institutes. It is also involved in licensing intellectual property rights to companies in collaboration with RIKEN Innovation.

If you are interested in the drug discovery themes and projects (pipeline table), we will first introduce to you the non-confidential information and subsequently disclose additional information upon the conclusion of a confidentiality agreement. The types of alliances include a licensing agreement for intellectual property rights and/or a joint research and development agreement to promote research and development together with the partner companies. In addition, it is also possible to consider other types of alliances in accordance with the requests of corporations.

Fig.2 Alliance Flow

About RIKEN Innovation Co., Ltd.

On September 5, 2019, RIKEN Innovation was established as a company wholly owned by RIKEN under a new law to promote science, technology, and innovation. RIKEN Innovation cooperates and collaborates closely with RIKEN, having the mission of rapidly returning research results as value to society and contributing to Japanese innovation.
Please refer to RIKEN Innovation web site for details.

Major alliances

Artificial adjuvant vector cell (aAVC) project
- Novel multifunctional cancer vaccine

We have developed a new cancer immunotherapy platform that induces innate and adaptive immunity. An investigator-initiated clinical trial for leukemia is currently underway. The licensing agreement has been executed with Astellas Pharma for specific antigens in oncology. Project Leader: Shinichiro Fujii

Cancer treatment project using iPS cell-derived NKT cells

We developed a method by utilizing iPS cell technology to amplify and induce NKT cells, which are T lymphocytes with strong antitumor activity. In 2020, ans investigator-initiated clinical trial targeting head and neck cancer was initiated at Chiba University. Project Leader: Haruhiko Koseki

Retinitis pigmentosa treatment project

For hereditary diseases in which the photoreceptor cells of the retina degenerate, we aimed to develop a treatment method that regenerates retinal function by transplanting iPS cell-derived retinal tissue. Clinical research was initiated in 2020 at the Kobe City Eye Center Hospital. Project Leader: Michiko Mandai

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