--------Past Studies--------------------
1. Optical imaging technique (intrinsic signal imaging) is a technique to detect local darkening of exposed cortex that reflects high metabolic changes caused by neural activity. ![]() a: Exposed cortex. scale bar, 1 mm.
b: Local darkening obtained by
subtracting an image before visual stimulation from the one during stimulation.
c: Stimulus. d: Statistical map showing activation
in b is statistically significant. e:
If statistically significant, contours are drawn at the half drop from the
peak of darkening (f).
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