Biofunctional Synthetic Chemistry Laboratory

田中生体機能合成化学研究室 • 理化学研究所

Papers:

  1. K. Tanaka, Development of Azaelectrocyclization-Based Labeling and Application to Noninvasive Imaging and Targeting Using N-Glycan Derivatives -In pursuit of N-Glycan Functions on Proteins, Dendrimers, and Living Cells-, Trends in Glycoscience and Glycotechnology, in press (2012).

  2. K. Tanaka, S. Shirotsuki, C. Kageyama, T. Tahara, S. Nozaki, E. R. O. Siwu, T. Iwata, S. Tamura, S. Douke, N. Murakami, H. Onoe, Y. Watanabe, K. Fukase, Template-Assisted and Self-Activating Clicked Peptide as a Synthetic Mimic of the SH2 Domain, ACS Chem. Biol., in press (2012).

  3. K. Tanaka, S. Yokoi, K. Morimoto, T. Iwata, Y. Nakamoto, K. Nakayama, K. Koyama, T. Fujiwara, K. Fukase, Cell Surface Biotinylation by Azaelectrocyclization: Easy-Handling and Versatile Approach for Living Cell Labeling, Bioorg. Med. Chem., 20, 1865–1868 (2012).

  4. K. Tanaka, K. Mazumder, E. R. O. Siwu, S. Nozaki, Y. Watanabe, K. Fukase, Auxiliary-Directed Oxidation of Ursolic Acid by “Ru”-Porphyrins: Chemical Modulation of Cytotoxicity against Tumor Cell Lines, Tetrahedron Lett., 53, 1756–1759 (2012).

  5. K. Tanaka, S. Katsumura, K. Fukase, Discovery and application of 6π-Azaelectrocyclization to natural product synthesis & synthetic biology, Sci. China Chem., 55, 19-30 (2012).

  6. T. Kobayashi, F. Hasegawa, Y. Hirose, K. Tanaka, H. Mori, S. Katsumura, Stereocontrolled Synthesis of Substituted Chiral Piperidines via One-Pot Asymmetric 6π-Azaelectrocyclization: Asymmetric Syntheses of (−)-Dendroprimine, (+)-7-Epidendroprimine, (+)-5-Epidendroprimine, and (+)-5,7-Epidendroprimine, J. Org. Chem., 77, 1812–1832 (2012).


Personal Accounts:

  1. 深瀬浩一, 田中克典, 糖鎖の生体内イメージング, バイオセンシング・バイオイメージングのニュートレンド-化学, in press, (2012).

  2. 深瀬浩一,田中克典, 糖鎖機能解明に向けた新規化学修飾反応：糖鎖とリンパ球のin vivo イメージング,『実験医学』, 疾患克服を目指した最新ケミカルバイオロジー, 30, in press, (2012).

  3. 深瀬浩一, 藤本ゆかり, 下山敦史, 田中克典, 細菌由来複合糖質の合成と自然免疫研究, 有機合成化学協会誌, 70, 113-130 (2012).


著書：

  1. K. Tanaka, K. Fukase, Chemical Approach to A Whole Body Imaging of Sialo-N-linked Glycans, In Topics in Current Chemistry volumes, SialoGlyco Chemistry and Biology, R. Gerardy-Schahn, P. Delannoy, and M. von Itzstein (eds), Springer, in press (2012).