Biofunctional Synthetic Chemistry Laboratory

田中生体機能合成化学研究室 • 理化学研究所

Papers:

  1. M. Kurosawa, K. Tanaka, K. Fukase, Asymmetric Synthesis of 14C-Labeled L-Propargylglycine, Radioisotopes, 59, 17-22 (2010).

  2. K. Tanaka, E. R. O. Siwu, K. Minami, K. Hasegawa, S. Nozaki, Y. Kanayama, K. Koyama, C. W. Chen, J. C. Paulson, Y. Watanabe, K. Fukase, Positron Emission Tomography (PET) and Fluorescence Imaging of Dendrimer-type N-Glycan Clusters: Remarkable Structural Dependency of Oligosaccharides on In Vivo Dynamics, Angew. Chem. Int. Ed., 49, 8195-8200 (2010).

  3. K. Tanaka, K. Minami, T. Tahara, E. R. O. Siwu, K. Koyama, S. Nozaki, H. Onoe, Y. Watanabe, K. Fukase, A Combined 6π-Azaelectrocyclization/Staudinger Approach to Protein & Cell Engineering: Non-Invasive Tumor Targeting by N-Glycan-Engineered Lymphocytes, J. Carbohydr. Chem., 29, 118-132 (2010).

  4. K. Tanaka, K. Minami, T. Tahara, Y. Fujii, E. R. O. Siwu, S. Nozaki, H. Onoe, S. Yokoi, K. Koyama, Y. Watanabe, K. Fukase, Electrocyclization-Based Labeling Allows Efficient In Vivo Imaging of Cellular Trafficking, ChemMedChem, 5, 841-845 (2010).

  5. K. Tanaka, In Vivo Imaging of Chemically Engineered Proteins and Cells by Oligosaccharides, Trends in Glycosci. Glycotechnol., 22, 48-50 (2010).

  6. G.-m. Bao, K. Tanaka, K. Ikenaka, K. Fukase, Probe Design & Synthesis of Galβ(1-3)[NeuAcα(2-6)]GlcNAcβ(1-2)Man Motif of N-Glycan, Bioorg. Med. Chem., 18, 3760-3766 (2010).

  7. K. Tanaka, K. Fukase, S. Katsumura, A New Strategy in Synthetic Biology: From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclization, Chem. Rec., 10, 119-139 (2010).


Personal Accounts:

  1. 田中克典, 深瀬浩一, 糖鎖の非侵襲的インビボイメージング, トランスレーショナルリサーチを支援する遺伝医学MOOK, 18, 66-73 (2010).

  2. 田中克典, 深瀬浩一, 高反応性アミノ基標識プローブの設計に基づく生体高分子の非侵襲撃的イメージング, 化学フロンティア2010: 生命現象を理解する分子ツール最前線-イメージングから生体機能解析まで-化学, 22, 54-62 (2010).

  3. 田中克典, 深瀬浩一, 糖鎖関連物質の非侵襲的インビボイメージングによる診断法開発への展望, 『生体の科学』, 61, 173-180 (2010).

  4. 田中克典, マイクロフロー反応を鍵とする生理活性天然物の実用的合成戦略, 有機合成化学協会誌, 68, 124-135 (2010).


著書：

  1. Y. Fujimoto, K. Tanaka, A. Shimoyama, K. Fukase, Self and Non-self Recognition with Bacterial and Animal Glycans, Surveys by Synthetic Chemistry, In Method in Enzymology, M. Fukuda (ed), Wiley, 478, 323-342 (2010).

  2. K. Tanaka, Y. Fujimoto, S. Tanaka, Y. Mori, K. Fukase, Combinatorial Methods in Oligosaccharide Synthesis, In Glycoscience, B. Fraser-Reid, K. Tatsuta, J. Thiem (eds), Springer, (2010).

  3. K. Tanaka, K. Fukase, Polymer-supported and Tag-assisted Methods in Oligosaccharide Synthesis, In Glycoscience, B. Fraser-Reid, K. Tatsuta, J. Thiem (eds), Springer, (2010).