Ph. D. (Engineering), Graduate School of Engineering, Yokohama National University
2000
M. A. (Engineering), Graduate School of Engineering, Yokohama National University
1998
B. S. (Engineering), Graduate School of Engineering, Yokohama National University
RESEARCH AND TEACHING EXPERIENCES
2014-present
Research Scientist, RIKEN
2013-2014
Contract researcher, RIKEN
2008-2013
Assistant Professor, Department of Chemistry and Biological Science, Aoyama Gakuin University.
2003-2008
Researcher, Graduate School of Information Science, Nagoya University.
AWARDS AND GRANTS
2007
Best Poster Award, the 3rd Asian Pacific Conference on Theoretical & Computational Chemistry, 2007, Beijing
2004
Excellent Research Award, 21st Century COE Program, "Frontiers of Computational Science", Nagoya University, 2004
PROFESSIONAL AFFILIATIONS
Chemical Society of Japan, The Biophysical Society of Japan, American Chemical Society,
Extramophiles Society of Japan, Cellulose Society of Japan
RESEARCH PROJECTS
Molecular dynamics simulation of cellular crowding environment
microscopic understanding of the life-sustaining mechanism of the extramophiles
PUBLICATIONS
（Papers）
Isseki Yu*, Kyoko Nakada, Masataka Nagaoka
Spatio-Temporal Characteristics of Transfer Free Energy of Apomyoglobin into the Crowding Condition with Trimethylamine N-oxide: A Study with Three Types of the Kirkwood-Buff Integral
Journal of Physical Chemistry B, 116, 4080−4088, (2012).
Isseki Yu*, Masayoshi Takayanagi, Masataka Nagaoka
Influence of Hydrostatic Pressure on Dynamics and Spatial Distribution of Protein Partial Molar Volume: Time-Resolved Surficial Kirkwood-Buff Approach
Journal of Physical Chemistry B, 114, 12392-12397, (2010)
Isseki Yu*, Masayoshi Takayanagi, Masataka Nagaoka
Intrinsic Alterations in the Partial Molar Volume on the Protein Denaturation:
Surficial Kirkwood−Buff Approach
Journal of Physical Chemistry B, 113, 3543-3547, (2009)
Isseki Yu, Masataka Nagaoka*
Surficial Kirkwood-Buff Approach on the Preferential Interaction of
Urea and Ectoine with Protein
Proceedings of International Symposium on Frontiers of Computational Science
2008, 9-14.
Eckhard Hitzer*, Kanta Tachibana, Sven Buchholz and Isseki Yu
Carrier Method for the General Evaluation and Control of Pose,
Molecular Conformation, Tracking, etc.
Advances in Applied Clifford Algebras Vol. 19(2), pp. 339-364 (2009)
Isseki Yu, Masataka Nagaoka*
Microscopic Understanding of Preferential Exclusion of Compatible Solute Ectoine:
Direct Interaction and Hydration Alteration
Journal of Physical Chemistry B, 111, 10231-10238, (2007).
Isseki Yu , Masataka Nagaoka*
Elongation of Water Residence Time at the Protein Interior in
Aqueous Solution with Ectoine
Frontiers of Computational Science (Springer, Berlin), 277-281, (2007).
Masayoshi Takayanagi, Isseki Yu, Masataka Nagaoka*
Theoretical Study on Stabilities of N-terminal Partial Chains from Apo-Myoglobin
Chemical Physics Letters, 421, 300-304, (2006).
Isseki Yu, Masataka Nagaoka*
Slowdown of Water Diffusion around Protein in Aqueous Solution with Ectoine
Chemical Physics Letters, 388, 316-321, (2004).
Isseki Yu, Kazuyosi Ueda*, Haruo Nakayama
Molecular Modeling of the Solvent Structuring of DMSO around Cellulose Triacetate
Bulletin of the Chemical Society of Japan, 76, 529-539, (2003).
Isseki Yu, Kazuyuki Iwata, Kazuyosi Ueda*, Haruo Nakayama
Molecular Modeling of the Solvent Structuring of Chloroform around Cellulose Triacetate
Bulletin of the Chemical Society of Japan, 76, 2285-2292, (2003).
Kazuyosi Ueda*, Taro Komai, Isseki Yu, Haruo Nakayama
Molecular Dynamics Study on the Density Fluctuation of Supercritical Water
Journal of Computer Chemistry, Japan, 1, 83-88, (2002).
（Reviews）
Masataka Nagaoka, Masayoshi Takayanagi, Isseki Yu,
Energy Flow Analysis in Proteins via Ensemble Molecular Dynamics Simulations:
Time-Resolved Vibrational Analysis and Surficial Kirkwood-Buff Theory
D.M. Leitner and J.E. Straub, Eds., "Proteins: Energy, Heat and Signal Flow", CRC, Boca Raton, 2009.
