Publications and patents of Arnout Voet
- Callewaert L, Van Herreweghe JM, Vanderkelen L, Leysen S, Voet A,
Michiels CW, (2012) “Guards of the great wall: bacterial lysozyme inhibitors”.
Trends in microbiology, in press.
- Helsen C, Marchand A, Chaltin P, Munck S, Voet A, Verstuyf A, Claessens F,
(2012) “Identification and Characterization of MEL-3, a Novel AR Antagonist
That Suppresses Prostate Cancer Cell Growth”.
Mol Cancer Ther, 2012 Jun;11(6):1257-68.
- Venken T, Daelemans D, De Maeyer M, Voet A, (2012)
“Computational investigation of the HIV-1 Rev multimerization using molecular
dynamics simulations and binding free energy calculations”.
Proteins, 2012 Jun;80(6):1633-46.
- Cavalluzzo C*, Voet A*, Christ F, Singh BK,Sharma A,Debyser Z,De
Maeyer M, and Van der Eycken E, (2011) “De Novo Design of Small
Molecule Inhibitors Targeting the LEDGF/p75-HIV Integrase
Interaction.” RSC Advances (epub ahead of publication:
DOI:10.1039/C1RA00582K) (*shared first author)
- Venken T, Krnavek T, M??nch J, Kirchhoff F, Henklein P, De Maeyer M,
and Voet A (2011), “An optimized MM/PBSA virtual screening approach
applied to an HIV-1 gp41 fusion peptide inhibitor.” Proteins:
Structure, Function, and Bioinformatics epub ahead of publication:
DOI: 10.1002/prot.23158
- Voet A*, Callewaert L*, Ulens T, Vanderkelen L, Vanherreweghe JM,
Michiels CW, and De Maeyer M. (2011). “Structure based discovery of
small molecule suppressors targeting bacterial lysozyme inhibitors”
Biochem Biophys Res Commun. 2011; 405(4):527-32. (shared first author)
(referee reading) (*shared first author)
- Hombrouck A, Clayton R, Voet A, Witvrouw M and Debyser Z (2011)
Resistance to Inhibitors of HIV-1 integrase. Book chapter in “HIV-1
Integrase: Mechanism and Inhibitor Design" (N. Neamati, Ed.), Wiley.
- Van Hecke K, Uytterhoeven K, Voet A, De Maeyer M, and Van Meervelt
L. (2010) “Designing Triple Helical Fragments: The Crystal Structure
of the Undecamer d(TGGCCTTAAGG) Mimicking T center dot AT Base
Triplets.” Crystal Growth & design 2010 10:10 4622-9 (referee
reading)
- Hendrix J, Gijsbers R, De Rijck J, Voet A, Hotta JI, McNeely M,
Hofkens J, Debyser Z, and Engelborghs Y. (2010) “The transcriptional
co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for
chromatin tethering.” Nucleic Acids Res. Oct 25. (referee reading)
- Christ F*, Voet A*, Marchand A*, Nicolet S, Desimmie B, Marchand D,
Bardiot D, Van der Veken N, Van Remoortel B, Strelkov S, De Maeyer M,
Chaltin P, and Debyser Z, (2010). “Rational design of small-molecule
inhibitors of the LEDGF/p75-integrase interaction and HIV
replication.” Nature Chemical Biology, 6(6), 442-448 (*shared first
author) (referee reading)
- Voet A, De Maeyer M, Christ F and Debyser Z , (2010) “Targeting
integration beyond strand transfer: development of second generation
HIV integrase inhibitors.” Bookchapter in Antiviral Drug Strategies
(E. De Clercq, ed.) (Wiley)
- Voet A, Marchand A, Debyser Z, De Maeyer M, Christ F, Chaltin P,
(2010) “Novel antiviral compounds” (2010 patent)
- Voet A, De Maeyer M, Debyser Z, and Christ F, (2009). “In search of
second generation HIV integrase inhibitors; targeting integration
beyond strand transfer”. Future Medicinal Chemistry, 1(7), 1259-1274
(referee reading)
- Vanlaer S, Voet A, Gielens C, De Maeyer M, and Compernolle F, (2009).
“Bridged 5,6,7,8-Tetrahydro-1,6-naphthyridines, Analogues of Huperzine
A: Synthesis, Modelling Studies and Evaluation as Inhibitors of
Acetylcholinesterase.” European journal of organic chemistry, (5),
643-654. (referee reading)
- Rombouts S, Fierens E, Vandermarliere E, Voet A, Gebruers K, Beaugrand
J, Courtin C, Delcour J, De Maeyer M, Rabijns A, Van Campenhout S, and
Volckaert G, (2009). “His22 of TLXI plays a critical role in the
inhibition of glycoside hydrolase family 11 xylanases.” Journal of
enzyme inhibition and medicinal chemistry, 24(1), 38-46 (referee
reading).
- Fierens E, Gebruers K, Voet A, De Maeyer M, Courtin C, and Delcour J,
(2009) “Biochemical and structural characterization of TLXI, the
Triticum aestivum L. thaumatin-like xylanase inhibitor.” Journal of
Enzyme Inhibition and Medicinal Chemistry, 24(3), 646-654 (referee
reading)
- Voet A, Smets W, Marchand D, Marchand A, Debyser Z, De Maeyer M,
Christ F, Chaltin P “Novel Viral Replication Inhibitors” (2009 patent)
- Voet A, Marchand A, Debyser Z, De Maeyer M, Christ F, Chaltin P,
“Novel Viral Replication Inhibitors” (2009 patent)
- Voet A, Marchand D, Marchand A, Debyser Z, De Maeyer M, Christ F,
Chaltin P, Bardiot D “Novel Viral Replication Inhibitors” (2009)
- Mont N, Mehta Pravinchandra V, Appukkuttan P, Beryozkina T, Toppet S,
Van Hecke K, Van Meervelt L, Voet A, De Maeyer M, and Van der Eycken
E, (2008). “Diversity oriented microwave-assisted synthesis of
(-)-Steganacin aza-analogues.” Journal of Organic Chemistry, 73(19),
7509-7516 (referee reading)
- Vanlaer S, De Borggraeve W, Voet A, Gielens C, De Maeyer M, and
Compernolle F, (2008). “Spirocyclic pyridoazepine analogues of
galanthamine: Synthesis, modelling studies and evaluation as
inhibitors of acetylcholinesterase.” European journal of organic
chemistry, (15), 2571-2581 (referee reading)
- Kamoune L, De Borggraeve W, Gielens C, Voet A, Robeyns K, De Maeyer M,
Van Meervelt L, Compernolle F, and Hoornaert G, (2007). “Design,
synthesis and evaluation of serine protease inhibitor analogues.”
European journal of organic chemistry, (18), 2977-2986 (referee
reading)
- Hombrouck A, De Rijck J, Hendrix J, Vandekerckhove L, Voet A, De
Maeyer M, Witvrouw M, Engelborghs Y, Christ F, Gijsbers R, and Debyser
Z, (2007). Virus evolution reveals an exclusive role for LEDGF/p75 in
chromosomal tethering of HIV. PLoS Pathogens, 3(3), e47 (referee
reading)
- Busschots K, Voet A, De Maeyer M, Rain, J, Emiliani S, Benarous R,
Desender L, Debyser Z, and Christ F, (2007). “Identification of the
LEDGF/p75 Binding Site in HIV-1 Integrase.” Journal of Molecular
Biology, 365(5), 1480-1492 (referee reading)
- Saerens S, Verstrepen K, Van Laere S, Voet A, Van Dijck P, Delvaux F,
and Thevelein J. (2006) “The Saccharomyces cerevisiae EHT1 and EEB1
Genes Encode Novel Enzymes with Medium-chain Fatty Acid Ethyl Ester
Synthesis and Hydrolysis Capacity.” J Biol Chem.
17;281(7):4446-56.(referee reading)