Power-free microfluidic devices

Poly(dimethylsiloxane) (PDMS) is widely used for structural material of microfluidic devices. Exploiting the high gas solubility of PDMS, we have realized an extremely easy micropumping method for PDMS devices. Since the energy for pumping is pre-stored in degassed bulk PDMS, this method requires no peripheral apparatus such as syringepump, electric power supply, tubing, and wiring. This method has been applied to the gold nanoparticle-based DNA analysis.



Power-free microfluidic devices




Hosokawa K, Omata M, and Maeda M: “Immunoassay on a Power-Free Microchip with Laminar Flow-Assisted Dendritic Amplification Anal. Chem., 79, 6000 (2007).


Hosokawa K, Omata M, Sato K, and Maeda M: Power-free sequential injection for microchip immunoassay toward point-of-care testing Lab on a Chip, 6, 236-241, (2006).


Hosokawa K, Sato K, Ichikawa N, and Maeda M: Power-free poly(dimethylsiloxane) microfluidic devices for gold nanoparticle-based DNA analysis, Lab on a Chip, 4, 181-185, (2004).