Paper

2018

  • Nakamura F, Kudo N, Tomachi Y, Nakata A, Takemoto M, Ito A, Tabei H, Arai D, de Voogd N, Yoshida M, Nakao Y, Fusetani N.
    Correction to: Halistanol sulfates I and J, new SIRT1-3 inhibitory steroid sulfates from a marine sponge of the genus Halichondria.
    J Antibiot (Tokyo). 2018 Mar;71(4):483.

  • Nakamura F, Kudo N, Tomachi Y, Nakata A, Takemoto M, Ito A, Tabei H, Arai D, de Voogd N, Yoshida M, Nakao Y, Fusetani N.
    Halistanol sulfates I and J, new SIRT1-3 inhibitory steroid sulfates from a marine sponge of the genus Halichondria.
    J Antibiot (Tokyo). 2018 Feb;71(2):273-278.

2017

  • Komiya M, Ito A, Endo M, Hiruma D, Hattori M, Saitoh H, Yoshida M, Ozawa T.
    A genetic screen to discover SUMOylated proteins in living mammalian cells.
    Sci Rep. 2017 Dec 12;7(1):17443.

  • Nelson J, Simpkins SW, Safizadeh H, Li SC, Piotrowski JS, Hirano H, Yashiroda Y, Osada H, Yoshida M, Boone C, Myers CL.
    MOSAIC: a chemical-genetic interaction data repository and web resource for exploring chemical modes of action.
    Bioinformatics. 2017 Nov 30.

  • Ueda M, Matsui A, Tanaka M, Nakamura T, Abe T, Sako K, Sasaki T, Kim JM, Ito A, Nishino N, Shimada H, Yoshida M, Seki M.
    The Distinct Roles of Class I and II RPD3-Like Histone Deacetylases in Salinity Stress Response.
    Plant Physiol. 2017 Dec;175(4):1760-1773.

  • Kuroki S, Okashita N, Baba S, Maeda R, Miyawaki S, Yano M, Yamaguchi M, Kitano S, Miyachi H, Itoh A, Yoshida M, Tachibana M.
    Rescuing the aberrant sex development of H3K9 demethylase Jmjd1a-deficient mice by modulating H3K9 methylation balance.
    PLoS Genet. 2017 Sep 26;13(9):e1007034.

  • Komine-Abe A, Nagano-Shoji M, Kubo S, Kawasaki H, Yoshida M, Nishiyama M, Kosono S.
    Effect of lysine succinylation on the regulation of 2-oxoglutarate dehydrogenase inhibitor, OdhI, involved in glutamate production in Corynebacterium glutamicum.
    Biosci Biotechnol Biochem. 2017 Nov;81(11):2130-2138.

  • Maeda K, Izawa M, Nakajima Y, Jin Q, Hirose T, Nakamura T, Koshino H, Kanamaru K, Ohsato S, Kamakura T, Kobayashi T, Yoshida M, Kimura M.
    Increased metabolite production by deletion of an HDA1-type histone deacetylase in the phytopathogenic fungi, Magnaporthe oryzae (Pyricularia oryzae) and Fusarium asiaticum.
    Lett Appl Microbiol. 2017 Nov;65(5):446-452.

  • Piotrowski JS, Li SC, Deshpande R, Simpkins SW, Nelson J, Yashiroda Y, Barber JM, Safizadeh H, Wilson E, Okada H, Gebre AA, Kubo K, Torres NP, LeBlanc MA, Andrusiak K, Okamoto R, Yoshimura M, van Leeuwen J, Shirahige K, Baryshnikova A, Brown GW, Hirano H, Costanzo M, Andrews B, Ohya Y, Osada H, Yoshida M, Myers CL, Boone C.
    Functional Annotation of Chemical Libraries across Diverse Biological Processes.
    Nat Chem Biol. 2017 Sep;13(9):982-993.

  • Bradshaw E, Yoshida M, Ling F.
    Regulation of Small Mitochondrial DNA Replicative Advantage by Ribonucleotide Reductase in Saccharomyces cerevisiae.
    G3 (Bethesda). 2017 Sep 7;7(9):3083-3090.

  • Noritsugu K, Ito A, Nakao Y, Yoshida M.
    Identification of zinc finger transcription factor EGR2 as a novel acetylated protein.
    Biochem Biophys Res Commun. 2017 Aug 5;489(4):455-459.

  • Takase S, Kurokawa R, Arai D, Kanemoto Kanto K, Okino T, Nakao Y, Kushiro T, Yoshida M, Matsumoto K.
    A quantitative shRNA screen identifies ATP1A1 as a gene that regulates cytotoxicity by aurilide B.
    Sci Rep. 2017 Sep;13(9):982-993.

  • Yoshida M, Kudo N, Kosono S, Ito A.
    Chemical and structural biology of protein lysine deacetylases. Review
    Proc Jpn Acad Ser B Phys Biol Sci. 2017;93(5):297-321.

  • Maeda K, Nakajima Y, Motoyama T, Kondoh Y, Kawamura T, Kanamaru K, Ohsato S, Nishiuchi T, Yoshida M, Osada H, Kobayashi T, Kimura M.
    Identification of a trichothecene production inhibitor by chemical array and library screening using trichodiene synthase as a target protein.
    Pestic Biochem Physiol. 2017 May;138:1-7.

  • Kurita K, Sakamoto T, Yagi N, Sakamoto Y, Ito A, Nishino N, Sako K, Yoshida M, Kimura H, Seki M, Matsunaga S.
    Live imaging of H3K9 acetylation in plant cells.
    Sci Rep. 2017 Apr 18;7:45894.

  • Nagano-Shoji M, Hamamoto Y, Mizuno Y, Yamada A, Kikuchi M, Shirouzu M, Umehara T, Yoshida M, Nishiyama M, Kosono S.
    Characterization of lysine acetylation of a phosphoenolpyruvate carboxylase involved in glutamate overproduction in Corynebacterium glutamicum.
    Mol Microbiol. 2017 May;104(4):677-689.

  • Sideri T, Yashiroda Y, Ellis DA, Rodríguez-López M, Yoshida M, Tuite MF, Bähler J.
    The copper transport-associated protein Ctr4 can form prion-like epigenetic determinants in Schizosaccharomyces pombe.
    Microb Cell. 2017 Jan;4(1):16-28.

  • Patanun O, Ueda M, Itouga M, Kato Y, Utsumi Y, Matsui A, Tanaka M, Utsumi C, Sakakibara H, Yoshida M, Narangajavana J, Seki M.
    The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Alleviates Salinity Stress in Cassava.
    Front Plant Sci. 2017 Jan 9;7:2039.

  • Matsuoka M, Kumar A, Muddassar M, Matsuyama A, Yoshida M, Zhang KY.
    Discovery of Fungal Denitrification Inhibitors by Targeting Copper Nitrite Reductase from Fusarium oxysporum.
    J Chem Inf Model. 2017 Feb 27;57(2):203-213.

  • Li G, Poulsen M, Fenyvuesvolgyi C, Yashiroda Y, Yoshida M, Simard JM, Gallo RC, Zhao RY.
    Characterization of cytopathic factors through genome-wide analysis of the Zika viral proteins in fission yeast.
    Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E376-E385.

  • Ishigaki Y, Akanuma G, Yoshida M, Horinouchi S, Kosono S, Ohnishi Y.
    Protein acetylation involved in streptomycin biosynthesis in Streptomyces griseus.
    J Proteomics. 2017 Feb 23;155:63-72.

  • Kubota T, Matsushita H, Tomita T, Kosono S, Yoshida M, Kuzuyama T, Nishiyama M.
    Novel stand-alone RAM domain protein-mediated catalytic control of anthranilate phosphoribosyltransferase in tryptophan biosynthesis in Thermus thermophilus.
    Extremophiles. 2017 Jan;21(1):73-83.

  • Yoshimoto R, Kaida D, Furuno M, Burroughs AM, Noma S, Suzuki H, Kawamura Y, Hayashizaki Y, Mayeda A, Yoshida M.
    Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A.
    RNA. 2017 Jan;23(1):47-57.

2016

  • Espiritu RA, Cornelio K, Kinoshita M, Matsumori N, Murata M, Nishimura S, Kakeya H, Yoshida M, Matsunaga S.
    Marine sponge cyclic peptide theonellamide A disrupts lipid bilayer integrity without forming distinct membrane pores.
    Biochim Biophys Acta. 2016 Jun;1858(6):1373-9.

  • Takemoto Y, Ito A, Niwa H, Okamura M, Fujiwara T, Hirano T, Handa N, Umehara T, Sonoda T, Ogawa K, Tariq M, Nishino N, Dan S, Kagechika H, Yamori T, Yokoyama S, Yoshida M.
    Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription.
    J Med Chem. 2016 Apr 28;59(8):3650-60.

  • Ling F, Niu R, Hatakeyama H, Goto Y, Shibata T, Yoshida M.
    Reactive oxygen species stimulate mitochondrial allele segregation toward homoplasmy in human cells.
    Mol Biol Cell. 2016 May 15;27(10):1684-93.

  • Fukuda I, Hirohama M, Ito A, Tariq M, Igarashi Y, Saitoh H, Yoshida M.
    Inhibition of protein SUMOylation by natural quinones.
    J Antibiot (Tokyo). 2016 Oct;69(10):776-779.

  • Nakata S, Watanabe T, Nakagawa K, Takeda H, Ito A, Fujimuro M.
    The dynamics of histone H2A ubiquitination in HeLa cells exposed to rapamycin, ethanol, hydroxyurea, ER stress, heat shock and DNA damage.
    Biochem Biophys Res Commun. 2016 Mar 25;472(1):46-52.

  • Sun X, Hirai G, Ueki M, Hirota H, Wang Q, Hongo Y, Nakamura T, Hitora Y, Takahashi H, Sodeoka M, Osada H, Hamamoto M, Yoshida M, Yashiroda Y.
    Identification of novel secreted fatty acids that regulate nitrogen catabolite repression in fission yeast.
    Sci Rep. 2016 Feb 19;6:20856.

  • Kumar A, Ito A, Hirohama M, Yoshida M, Zhang KY.
    Identification of new SUMO activating enzyme 1 inhibitors using virtual screening and scaffold hopping.
    Bioorg Med Chem Lett. 2016 Feb 15;26(4):1218-23.

  • Tariq M, Ito A, Ishfaq M, Bradshaw E, Yoshida M.
    Eukaryotic translation initiation factor 5A (eIF5A) is essential for HIF-1α activation in hypoxia.
    Biochem Biophys Res Commun. 2016 Feb 5;470(2):417-24.

  • Vo TV, Das J, Meyer MJ, Cordero NA, Akturk N, Wei X, Fair BJ, Degatano AG, Fragoza R, Liu LG, Matsuyama A, Trickey M, Horibata S, Grimson A, Yamano H, Yoshida M, Roth FP, Pleiss JA, Xia Y, Yu H.
    A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
    Cell. 2016 Jan 14;164(1-2):310-23.

  • Mizuno Y, Nagano-Shoji M, Kubo S, Kawamura Y, Yoshida A, Kawasaki H, Nishiyama M, Yoshida M, Kosono S.
    Altered acetylation and succinylation profiles in Corynebacterium glutamicum in response to conditions inducing glutamate overproduction.
    Microbiologyopen. 2016 Feb;5(1):152-73.

  • Sako K, Kim JM, Matsui A, Nakamura K, Tanaka M, Kobayashi M, Saito K, Nishino N, Kusano M, Taji T, Yoshida M, Seki M.
    Ky-2, a Histone Deacetylase Inhibitor, Enhances High-Salinity Stress Tolerance in Arabidopsis thaliana.
    Plant Cell Physiol. 2016 Apr;57(4):776-83.

  • Larrayoz M, Blakemore SJ, Dobson RC, Blunt MD, Rose-Zerilli MJ, Walewska R, Duncombe A, Oscier D, Koide K, Forconi F, Packham G, Yoshida M, Cragg MS, Strefford JC, Steele AJ.
    The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1.
    Leukemia. 2016 Feb;30(2):351-60.

  • Kakeya H, Kaida D, Sekiya H, Nagai K, Yoshida M, Osada H.
    RQN-18690A (18-deoxyherboxidiene) targets SF3b, a spliceosome component, and inhibits angiogenesis.
    J Antibiot (Tokyo). 2016 Feb;69(2):121-3.

  • Nakaoka S, Sasaki K, Ito A, Nakao Y, Yoshida M.
    A Genetically Encoded FRET Probe to Detect Intranucleosomal Histone H3K9 or H3K14 Acetylation Using BRD4, a BET Family Member.
    ACS Chem Biol. 2016 Mar 18;11(3):729-33.

  • A. Kurata, A. Fujiwara, N. Haruyama, T. Tsuchida
    Multiplex PCR method for rapid identification of genetic group and symbiont infection status in Bemisia tabaci (Hemiptera: Aleyrodidae)
    Applied Entomology and Zoology February 2016, Volume 51, Issue 1, pp 167–172

2015

  • Ito A, Shimazu T, Maeda S, Shah AA, Tsunoda T, Iemura S, Natsume T, Suzuki T, Motohashi H, Yamamoto M, Yoshida M.
    The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1.
    Sci Signal. 2015 Nov 24;8(404)

  • Abe N, Matsumoto K, Nishihara M, Nakano Y, Shibata A, Maruyama H, Shuto S, Matsuda A, Yoshida M, Ito Y, Abe H.
    Rolling Circle Translation of Circular RNA in Living Human Cells.
    Sci Rep. 2015 Nov 10;5:16435.

  • Shahidul Islam M, Nurul Islam M, Ashraful Hoque M, Nishino N, Kato T, Kim HJ, Ito A, Yoshida M.
    An efficient synthesis of SK-658 and its analogs as potent histone deacetylase inhibitors.
    Bioorg Chem. 2015 Apr;59:145-50.

  • De Clerck C, Fujiwara A, Joncour P, Léonard S, Félix ML, Francis F, Jijakli MH, Tsuchida T, Massart S.
    A metagenomic approach from aphid's hemolymph sheds light on the potential roles of co-existing endosymbionts.
    Microbiome. 2015 Dec 15;3:63.

  • Serate J, Xie D, Pohlmann E, Donald C Jr, Shabani M, Hinchman L, Higbee A, Mcgee M, La Reau A, Klinger GE, Li S, Myers CL, Boone C, Bates DM, Cavalier D, Eilert D, Oates LG, Sanford G, Sato TK, Dale B, Landick R, Piotrowski J, Ong RG, Zhang Y.
    Controlling microbial contamination during hydrolysis of AFEX-pretreated corn stover and switchgrass: effects on hydrolysate composition, microbial response and fermentation.
    Biotechnol Biofuels. 2015 Nov 14;8:180.

  • Lu J, Jiang C, Li X, Jiang L, Li Z, Schneider-Poetsch T, Liu J, Yu K, Liu JO, Jiang H, Luo C, Dang Y.
    A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation.
    Nucleic Acids Res. 2015 Dec 2;43(21):10157-67.

  • Kobayashi H, Nishimura H, Matsumoto K, Yoshida M.
    Identification of the determinants of 2-deoxyglucose sensitivity in cancer cells by shRNA library screening.
    Biochem Biophys Res Commun. 2015 Nov 6;467(1):121-7.

  • Okuda K, Ito A, Uehara T.
    Regulation of Histone Deacetylase 6 Activity via S-Nitrosylation.
    Biol Pharm Bull. 2015;38(9):1434-7.

  • Nakajima Y, Koseki N, Sugiura R, Tominaga N, Maeda K, Tokai T, Izawa M, Kanamaru K, Kamakura T, Kobayashi T, Nishiuchi T, Yoshida M, Kimura M.
    Effect of disrupting the trichothecene efflux pump encoded by FgTri12 in the nivalenol chemotype of Fusarium graminearum.
    J Gen Appl Microbiol. 2015;61(3):93-6.

  • Kosono S, Tamura M, Suzuki S, Kawamura Y, Yoshida A, Nishiyama M, Yoshida M.
    Changes in the Acetylome and Succinylome of Bacillus subtilis in Response to Carbon Source.
    PLoS One. 2015 Jun 22;10(6):e0131169.

  • Arita Y, Nishimura S, Ishitsuka R, Kishimoto T, Ikenouchi J, Ishii K, Umeda M, Matsunaga S, Kobayashi T, Yoshida M.
    Targeting cholesterol in a liquid-disordered environment by theonellamides modulates cell membrane order and cell shape.
    Chem Biol. 2015 May 21;22(5):604-10.

  • Piotrowski JS, Okada H, Lu F, Li SC, Hinchman L, Ranjan A, Smith DL, Higbee AJ, Ulbrich A, Coon JJ, Deshpande R, Bukhman YV, McIlwain S, Ong IM, Myers CL, Boone C, Landick R, Ralph J, Kabbage M, Ohya Y.
    Plant-derived antifungal agent poacic acid targets β-1,3-glucan.
    Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1490-7.

  • Bai D, Nakao R, Ito A, Uematsu H, Senpuku H.
    Immunoreactive antigens recognized in serum samples from mice intranasally immunized with Porphyromonas gingivalis outer membrane vesicles.
    Pathog Dis. 2015 Apr;73(3).

  • Milite C, Feoli A, Sasaki K, La Pietra V, Balzano AL, Marinelli L, Mai A, Novellino E, Castellano S, Tosco A, Sbardella G.
    A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach.
    J Med Chem. 2015 Mar 26;58(6):2779-98.

  • Feldman JL, Dittenhafer-Reed KE, Kudo N, Thelen JN, Ito A, Yoshida M, Denu JM.
    Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation.
    Biochemistry. 2015 May 19;54(19):3037-50.

  • Scully OJ, Yu Y, Salim A, Thike AA, Yip GW, Baeg GH, Tan PH, Matsumoto K, Bay BH.
    Complement component 1, q subcomponent binding protein is a marker for proliferation in breast cancer.
    Exp Biol Med (Maywood). 2015 Jul;240(7):846-53.

  • Le Bescont A, Vitte AL, Debernardi A, Curtet S, Buchou T, Vayr J, de Reyniès A, Ito A, Guardiola P, Brambilla C, Yoshida M, Brambilla E, Rousseaux S, Khochbin S.
    Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies.
    Antioxid Redox Signal. 2015 Jul 1;23(1):1-14.

2014

  • Hoque MA, Islam MS, Islam MN, Kato T, Nishino N, Ito A, Yoshida M.
    Design and synthesis of mono and bicyclic tetrapeptides thioester as potent inhibitor of histone deacetylases.
    Amino Acids. 2014 Oct;46(10):2435-44.

  • Islam MN, Islam MS, Hoque MA, Kato T, Nishino N, Ito A, Yoshida M.
    Bicyclic tetrapeptides as potent HDAC inhibitors: effect of aliphatic loop position and hydrophobicity on inhibitory activity.
    Bioorg Med Chem. 2014 Aug 1;22(15):3862-70.

  • Koga M, Satoh T, Takasaki I, Kawamura Y, Yoshida M, Kaida D.
    U2 snRNP is required for expression of the 3' end of genes.
    PLoS One. 2014 May 20;9(5):e98015.

  • Miyagawa K, Low RS, Santosa V, Tsuji H, Moser BA, Fujisawa S, Harland JL, Raguimova ON, Go A, Ueno M, Matsuyama A, Yoshida M, Nakamura TM, Tanaka K.
    SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.
    Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):5950-5.

  • Fukui Y, Narita K, Dan S, Yamori T, Ito A, Yoshida M, Katoh T.
    Total synthesis of burkholdacs A and B and 5,6,20-tri-epi-burkholdac A: HDAC inhibition and antiproliferative activity.
    Eur J Med Chem. 2014 Apr 9;76:301-13.

  • Khan K, Schneider-Poetsch T, Ishfaq M, Ito A, Yoshimoto R, Mukaida N, Yoshida M.
    Splicing inhibition induces gene expression through canonical NF-κB pathway and extracellular signal-related kinase activation.
    FEBS Lett. 2014 Mar 18;588(6):1053-7.

  • Kumar A, Ito A, Takemoto M, Yoshida M, Zhang KY.
    Identification of 1,2,5-oxadiazoles as a new class of SENP2 inhibitors using structure based virtual screening.
    J Chem Inf Model. 2014 Mar 24;54(3):870-80.

  • Takemoto M, Kawamura Y, Hirohama M, Yamaguchi Y, Handa H, Saitoh H, Nakao Y, Kawada M, Khalid K, Koshino H, Kimura K, Ito A, Yoshida M.
    Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata.
    J Antibiot (Tokyo). 2013 Jul;11(7):689-98.

2013

  • Nishimura S, Ishii K, Iwamoto K, Arita Y, Matsunaga S, Ohno-Iwashita Y, Sato SB, Kakeya H, Kobayashi T, Yoshida M.
    Visualization of sterol-rich membrane domains with fluorescently-labeled theonellamides.
    PLoS One. 2013 Dec 27;8(12):e83716.

  • Fustin JM, Doi M, Yamaguchi Y, Hida H, Nishimura S, Yoshida M, Isagawa T, Morioka MS, Kakeya H, Manabe I, Okamura H.
    RNA-methylation-dependent RNA processing controls the speed of the circadian clock.
    Cell. 2013 Nov 7;155(4):793-806.

  • Hirohama M, Kumar A, Fukuda I, Matsuoka S, Igarashi Y, Saitoh H, Takagi M, Shin-ya K, Honda K, Kondoh Y, Saito T, Nakao Y, Osada H, Zhang KY, Yoshida M, Ito A.
    Spectomycin B1 as a novel SUMOylation inhibitor that directly binds to SUMO E2.
    ACS Chem Biol. 2013 Dec 20;8(12):2635-42.

  • Hao R, Nanduri P, Rao Y, Panichelli RS, Ito A, Yoshida M, Yao TP.
    Proteasomes activate aggresome disassembly and clearance by producing unanchored ubiquitin chains.
    Mol Cell. 2013 Sep 26;51(6):819-28.

  • Nakajima Y, Kawamura T, Maeda K, Ichikawa H, Motoyama T, Kondoh Y, Saito T, Kobayashi T, Yoshida M, Osada H, Kimura M.
    Identification and characterization of an inhibitor of trichothecene 3-O-acetyltransferase, TRI101, by the chemical array approach.
    Biosci Biotechnol Biochem. 2013;77(9):1958-60.

  • Deshpande R, Asiedu MK, Klebig M, Sutor S, Kuzmin E, Nelson J, Piotrowski J, Shin SH, Yoshida M, Costanzo M, Boone C, Wigle DA, Myers CL.
    A comparative genomic approach for identifying synthetic lethal interactions in human cancer.
    Cancer Res. 2013 Oct 15;73(20):6128-36.

  • Kumar A, Ito A, Hirohama M, Yoshida M, Zhang KY.
    Identification of quinazolinyloxy biaryl urea as a new class of SUMO activating enzyme 1 inhibitors.
    Bioorg Med Chem Lett. 2013 Sep 15;23(18):5145-9.

  • Arai T, Ashraful Hoque M, Nishino N, Kim HJ, Ito A, Yoshida M.
    Cyclic tetrapeptides with -SS- bridging between amino acid side chains for potent histone deacetylases' inhibition.
    Amino Acids. 2013 Oct;45(4):835-43.

  • Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.
    Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".
    Sci Transl Med. 2013 Jun 5;5(188):188lr2.

  • Yoshida M, Ohnuki S, Yashiroda Y, Ohya Y.
    Profilin is required for Ca2+ homeostasis and Ca2+-modulated bud formation in yeast.
    Mol Genet Genomics. 2013 Aug;288(7-8):317-28.

  • Das J, Vo TV, Wei X, Mellor JC, Tong V, Degatano AG, Wang X, Wang L, Cordero NA, Kruer-Zerhusen N, Matsuyama A, Pleiss JA, Lipkin SM, Yoshida M, Roth FP, Yu H.
    Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
    Sci Signal. 2013 May 21;6(276):ra38.

  • Guo TT, Yu YN, Cheong Yip GW, Matsumoto K, Bay BH.
    Silencing the YB-1 gene inhibits cell migration in gastric cancer in vitro.
    Anat Rec (Hoboken). 2013 Jun;296(6):891-8.

  • Ling F, Hori A, Yoshitani A, Niu R, Yoshida M, Shibata T.
    Din7 and Mhr1 expression levels regulate double-strand-break-induced replication and recombination of mtDNA at ori5 in yeast.
    Nucleic Acids Res. 2013 Jun;41(11):5799-816.

  • Matsushita K, Tamura M, Tanaka N, Tomonaga T, Matsubara H, Shimada H, Levens D, He L, Liu J, Yoshida M, Nomura F.
    Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression.
    Mol Cancer Res. 2013 Jul;11(7):689-98.

  • Matsubara K, Lee AR, Kishigami S, Ito A, Matsumoto K, Chi H, Nishino N, Yoshida M, Hosoi Y.
    Dynamics and regulation of lysine-acetylation during one-cell stage mouse embryos.
    Biochem Biophys Res Commun. 2013 Apr 26;434(1):1-7.

  • Kumar A, Ito A, Hirohama M, Yoshida M, Zhang KY.
    Identification of sumoylation activating enzyme 1 inhibitors by structure-based virtual screening.
    J Chem Inf Model. 2013 Apr 22;53(4):809-20.

  • Espiritu RA, Matsumori N, Murata M, Nishimura S, Kakeya H, Matsunaga S, Yoshida M.
    Interaction between the marine sponge cyclic peptide theonellamide A and sterols in lipid bilayers as viewed by surface plasmon resonance and solid-state (2)H nuclear magnetic resonance.
    Biochemistry. 2013 Apr 9;52(14):2410-8.

  • Kawaguchi M, Yasumasu S, Shimizu A, Kudo N, Sano K, Iuchi I, Nishida M.
    Adaptive evolution of fish hatching enzyme: one amino acid substitution results in differential salt dependency of the enzyme.
    J Exp Biol. 2013 May 1;216(Pt 9):1609-15.

  • Narita K, Fukui Y, Sano Y, Yamori T, Ito A, Yoshida M, Katoh T.
    Total synthesis of bicyclic depsipeptides spiruchostatins C and D and investigation of their histone deacetylase inhibitory and antiproliferative activities.
    Eur J Med Chem. 2013 Feb;60:295-304.

2012

  • Ishfaq M, Maeta K, Maeda S, Natsume T, Ito A, Yoshida M.
    The role of acetylation in the subcellular localization of an oncogenic isoform of translation factor eIF5A.
    Biosci Biotechnol Biochem. 2012;76(11):2165-7.

  • Hoque MA, Arai T, Nishino N, Kim HJ, Ito A, Yoshida M.
    Cyclic tetrapeptides with thioacetate tails or intramolecular disulfide bridge as potent inhibitors of histone deacetylases.
    Bioorg Med Chem Lett. 2012 Nov 1;22(21):6770-2.

  • Takahashi H, Sun X, Hamamoto M, Yashiroda Y, Yoshida M.
    The SAGA histone acetyltransferase complex regulates leucine uptake through the Agp3 permease in fission yeast.
    J Biol Chem. 2012 Nov 2;287(45):38158-67.

  • Cho HS, Shimazu T, Toyokawa G, Daigo Y, Maehara Y, Hayami S, Ito A, Masuda K, Ikawa N, Field HI, Tsuchiya E, Ohnuma S, Ponder BA, Yoshida M, Nakamura Y, Hamamoto R.
    Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
    Nat Commun. 2012;3:1072.

  • Bauer F, Matsuyama A, Yoshida M, Hermand D.
    Determining proteome-wide expression levels using reverse protein arrays in fission yeast.
    Nat Protoc. 2012 Oct;7(10):1830-5.

  • Dancy BM, Crump NT, Peterson DJ, Mukherjee C, Bowers EM, Ahn YH, Yoshida M, Zhang J, Mahadevan LC, Meyers DJ, Boeke JD, Cole PA.
    Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition.
    Chembiochem. 2012 Sep 24;13(14):2113-21.

  • Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.
    Drug screening for ALS using patient-specific induced pluripotent stem cells.
    Sci Transl Med. 2012 Aug 1;4(145):145ra104.

  • Niu R, Yoshida M, Ling F.
    Increases in mitochondrial DNA content and 4977-bp deletion upon ATM/Chk2 checkpoint activation in HeLa cells.
    PLoS One. 2012;7(7):e40572.

  • Ishfaq M, Maeta K, Maeda S, Natsume T, Ito A, Yoshida M.
    Acetylation regulates subcellular localization of eukaryotic translation initiation factor 5A (eIF5A).
    FEBS Lett. 2012 Sep 21;586(19):3236-41.

  • Bauer, F., Matsuyama, A., Candiracci, J., Dieu, M., Scheliga, J., Wolf, D. A., Yoshida, M., and Hermand, D.
    Translational control of cell division by Elongator.
    Cell Rep. 2012 May 31;1(5):424-33.

  • Isozaki Y, Hoshino I, Nohata N, Kinoshita T, Akutsu Y, Hanari N, Mori M, Yoneyama Y, Akanuma N, Takeshita N, Maruyama T, Seki N, Nishino N, Yoshida M, Matsubara H.
    Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma.
    Int J Oncol. 2012 Oct;7(10):1830-5.

  • Yoshihara H, Fukushima T, Hakuno F, Saeki Y, Tanaka K, Ito A, Yoshida M, Iemura S, Natsume T, Asano T, Chida K, Girnita L, Takahashi S.
    Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs.
    Biochem Biophys Res Commun. 2012 Jun 22;423(1):122-7.

  • Bradshaw E, Yoshida M, Ling F.
    Mitochondrial fission proteins Fis1 and Mdv1, but not Dnm1, play a role in maintenance of heteroplasmy in budding yeast.
    FEBS Lett. 2012 Sep;41(3):985-94.

  • Kamemura K, Ogawa M, Ohkubo S, Ohtsuka Y, Shitara Y, Komiya T, Maeda S, Ito A, Yoshida M.
    Depression of mitochondrial metabolism by downregulation of cytoplasmic deacetylase, HDAC6.
    FEBS Lett. 2012 May 7;586(9):1379-83.

  • Matsushita, K., Kajiwara, T., Tamura, M., Satoh, M., Tanaka, N., Tomonaga, T., Matsubara, H., Shimada, H., Yoshimoto, R., Ito, A., Kubo, S., Natsume, T., Levens, D., Yoshida, M., and Nomura, F.
    SAP155-mediated splicing of FUSE-binding protein-interacting repressor (FIR) serves as a molecular switch for c-myc gene expression.
    Mol. Cancer Res. 2012 Apr 11.

  • Kobayashi H, Harada H, Nakamura M, Futamura Y, Ito A, Yoshida M, Iemura S, Shin-Ya K, Doi T, Takahashi T, Natsume T, Imoto M, Sakakibara Y.
    Comprehensive predictions of target proteins based on protein-chemical interaction using virtual screening and experimental verifications.
    BMC Chem Biol. 2012 Apr 5;12:2.

  • Piotrowski JS, Nagarajan S, Kroll E, Stanbery A, Chiotti KE, Kruckeberg AL, Dunn B, Sherlock G, Rosenzweig F.
    Different selective pressures lead to different genomic outcomes as newly-formed hybrid yeasts evolve.
    BMC Evol Biol. 2012 Apr 2;12:46.

  • Osada, H., Muroi, M., and Yoshida, M.
    The chemistry/biology interface.
    Bioorg. Med. Chem. 2012 Mar 15;20(6):1844-5.

  • Takahashi, M., Takemoto, Y., Shimazu, T., Kawasaki, H., Tachibana, M., Shinkai, Y., Takagi, M., Shin-Ya, K., Igarashi, Y., Ito, A., and Yoshida, M.
    Inhibition of histone H3K9 methyltransferases by gliotoxin and related epipolythiodioxopiperazines.
    J. Antibiot. 2012 Feb 15.

  • Sasaki, K., Ito, A., and Yoshida, M.
    Development of live-cell imaging probes for monitoring histone modifications.
    Bioorg. Med. Chem. 2012 Mar 15;20(6):1887-92.

  • Matsuyama, A. and Yoshida, M.
    Heterologous gene expression by chromosomal integration in fission yeast.
    Methods Mol. Biol. 2012;824:433-50.

  • Sun, Y., Takada, K., Takemoto, Y., Yoshida, M., Nogi, Y., Okada, S., and Matsunaga, S.
    Gliotoxin analogues from a marine-derived fungus, Penicillium sp., and their cytotoxic and histone methyltransferase inhibitory activities.
    J. Nat. Prod. 2012 Jan 27;75(1):111-4.

2011

  • Williams DE, Dalisay DS, Patrick BO, Matainaho T, Andrusiak K, Deshpande R, Myers CL, Piotrowski JS, Boone C, Yoshida M, Andersen RJ.
    Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment.
    Org Lett. 2011 Aug 5;13(15):3936-9.

  • Fukushima T, Okajima H, Yamanaka D, Ariga M, Nagata S, Ito A, Yoshida M, Asano T, Chida K, Hakuno F, Takahashi S.
    HSP90 interacting with IRS-2 is involved in cAMP-dependent potentiation of IGF-I signals in FRTL-5 cells.
    Mol Cell Endocrinol. 2011 Mar 4;406(1):42-6.

  • Tsuiji, H., Yoshimoto, R., Hasegawa, Y., Furuno, M., Yoshida, M., and Nakagawa, S.
    Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor-1.
    Genes Cells. 2011 May;16(5):479-90.

  • Takahashi, H., Suzuki, T., Shirai, A., Matsuyama, A., Dohmae, N., and Yoshida, M.
    Mitochondrial localization of fission yeast manganese superoxide dismutase is required for its lysine acetylation and for cellular stress resistance and respiratory growth.
    Biochem. Biophys. Res. Commun. 2011 Mar 4;406(1):42-6.

  • Schmidt, U., Basyuk, E., Robert, M.-C., Yoshida, M., Villemin, J.-P., Auboeuf, D., Aitken, S., and Bertrand, E.
    Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation.
    J. Cell Biol. 2011 May 30;193(5):819-29.

  • Oiso, H., Furukawa, N., Suefuji, M., Shimoda, S., Ito, A., Furumai, R., Nakagawa, J., Yoshida, M., Nishino, N., and Araki, E.
    The role of class I histone deacetylase (HDAC) on gluconeogenesis in liver.
    Biochem. Biophys. Res. Commun. 2011 Jan 7;404(1):166-72.

  • Martins, S. B., Rino, J., Carvalho, T., Carvalho, C., Yoshida, M., Klose, J. M., Almeida, S. F. d., and Carmo-Fonseca, M.
    Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3′ end of human genes.
    Nat. Str. Mol Biol. 2011 Sep 4;18(10):1115-23.

  • Kizuka, Y., Kitazume, S., Yoshida, M., and Taniguchi, N.
    Brain-specific Expression of N-Acetylglucosaminyltransferase IX (GnT-IX) Is Regulated by Epigenetic Histone Modifications.
    J. Biol. Chem. 2011 Sep 9;286(36):31875-84.

  • Ito, T., Umehara, T., Sasaki, K., Nakamura, Y., Nishino, N., Terada, T., Shirouzu, M., Padmanabhan, B., Yokoyama, S., Ito, A., and Yoshida, M.
    Real-time imaging of histone H4K12-specific acetylation determines the modes of action of histone deacetylase and bromodomain inhibitors.
    Chem. Biol. 2011 Apr 22;18(4):495-507.

  • Islam, M. S., Bhuiyan, M. P., Islam, M. N., Nsiama, T. K., Oishi, N., Kato, T., Nishino, N., Ito, A., and Yoshida, M.
    Evaluation of functional groups on amino acids in cyclic tetrapeptides in histone deacetylase inhibition.
    Amino Acids. 2011 Jun 3.

  • Hori, A., Yoshida, M., and Ling, F.
    Mitochondrial fusion increases the mitochondrial DNA copy number in budding yeast.
    Genes Cells. 2011 May;16(5):527-44.

  • Hasegawa, M., Miura, T., Kuzuya, K., Inoue, A., Ki, S. W., Horinouchi, S., Yoshida, T., Kunoh, T., Koseki, K., Mino, K., Sasaki, R., Yoshida, M., and Mizukami, T.
    Identification of SAP155 as the target of GEX1A (Herboxidiene), an antitumor natural product.
    ACS Chem. Biol. 2011 Sep 4;18(10):1115-23.

  • Furumai, R., Ito, A., Ogawa, K., Maeda, S., Saito, A., Nishino, N., Horinouchi, S., and Yoshida, M.
    Histone deacetylase inhibitors block NF-κB−dependent transcription by interfering with RNA polymerase II recruitment.
    Cancer Sci. 2011 May;102(5):1081-7.

  • Furukawa, K., Abe, H., Tamura, Y., Yoshimoto, R., Yoshida, M., Tsuneda, S., and Ito, Y.
    Fluorescence detection of intron lariat RNA with reduction-triggered fluorescent probes.
    Angew. Chem. Int. Ed. 2011 Dec 9;50(50):12020-3.

  • Arita, Y., Nishimura, S., Matsuyama, A., Yashiroda, Y., Usui, T., Boone, C., and Yoshida, M.
    Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.Evaluation of functional groups on amino acids in cyclic tetrapeptides in histone deacetylase inhibition.
    Mol. BioSyst. 2011 May;7(5):1463-72.

2010

  • Furumai R, Uchida K, Komi Y, Yoneyama M, Ishigami K, Watanabe H, Kojima S, Yoshida M
    Spliceostatin A blocks angiogenesis by inhibiting global gene expression including VEGF.
    Cancer Sci. 2010 Nov;101(11).

  • Iwasa, E., Hamashima, Y., Fujishiro, S., Higuchi, E., Ito, A., Yoshida, M., and Sodeoka, M.
    Total synthesis of (+)-chaetocin and its analogs: Their histone methyltransferase G9a inhibitory activity.
    J Am Chem Soc. 2010 Mar 31;132(12):4078-9.

  • Jung, I., Matsuyama, A., Yoshida, M., and Kim, D.
    PostMod: sequence based prediction of kinase-specific phosphorylation sites with indirect relationship.
    BMC Bioinformatics. 2010 Jan 18;11.

  • Islam, N. M., Kato, T., Nishino, N., Kim, H.-J., Ito, A., and Yoshida, M.
    Bicyclic peptides as potent inhibitors of histone deacetylases: Optimization of alkyl loop length.
    Bioorg Med Chem Lett. 2010 Feb 1;20(3):997-9.

  • Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H., and Yoshida, M.
    A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor.
    Biochem Biophys Res Commun. 2010 Apr 9;394(3):569-73.

  • Schneider-Poetsch, T., Usui, T., Kaida, D., and Yoshida, M.
    Garbled messages and corrupted translations.
    Nat Chem Biol. 2010 Mar;6(3):189-198.

  • Murakami, K., Matsubara, H., Hoshino, I., Akutsu, Y., Miyazawa, Y., Matsushita, K., Sakata, H., Nishimori, T., Usui, A., Kano, M., Nishino, N., and Yoshida, M.
    CHAP31 induces apoptosis only via the intrinsic pathway in human esophageal cancer cells.
    Oncology. 2010;78(1):62-74. Epub 2010 Mar 6.

  • Nishimura, S., Arita, Y., Honda, M., Iwamoto, K., Matsuyama, A., Shirai, A., Kawasaki, H., Kakeya, H., Kobayashi, T., Matsunaga, S., and Yoshida, M.
    Marine antifungal theonellamides target 3b-hydroxysterol to activate Rho1 signaling.
    Nature Chem. Biol. 2010 Jul;6(7).

  • Yoshida, M., Takeuchi, H., Ishida, Y., Yashiroda, Y., Yoshida, M., Takagi, M., Shin-Ya, K., and Doi, T.
    Synthesis, structure determination, and biological evaluation of destruxin E.
    Org. Lett. 2010 Sep 3;12(17):3792-5.

2009

  • Izawa, M., Takekawa, O., Arie, T., Teraoka, T., Yoshida, M., Kimura, M., and Kamakura, T.
    Inhibition of histone deacetylase causes reduction of appressorium formation in the rice blast fungus Magnaporthe oryzae.
    J. Gen. Appl. Microbiol. 2009 Sep 22;106(38):16257-62.

  • Sasaki, K., Ito, T., Nishino, N., Khochbin, S., and Yoshida, M.
    Real-time imaging of histone H4 hyperacetylation in living cells.
    Proc. Natl. Acad. Sci. U.S.A. 2009 Sep 22;106(38):16257-62.

  • Sato, M., Okada, N., Kakui, Y., Yamamoto, M., Yoshida, M., and Toda, T.
    Nucleocytoplasmic transport of Alp7/TACC organizes spatiotemporal microtubule formation in fission yeast.
    EMBO Rep. 2009 Aug 21.

  • Ho CH, Magtanong L, Barker SL, Gresham D, Nishimura S, Natarajan P, Koh JL, Porter J, Gray CA, Andersen RJ, Giaever G, Nislow C, Andrews B, Botstein D, Graham TR, Yoshida M, Boone C.
    A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds.
    Nat Biotechnol. 2009 Apr;27(4):369-77.

  • Ueda JY, Hwang JH, Maeda S, Kato T, Ochiai A, Isshiki K, Yoshida M, Takagi M, Shin-Ya K.
    JBIR-17, a novel trichostatin analog from Streptomyces sp. 26634.
    J Antibiot (Tokyo). 2009 May;62(5):283-5.

  • Fukuda I, Ito A, Uramoto M, Saitoh H, Kawasaki H, Osada H, Yoshida M.
    Kerriamycin B inhibits protein SUMOylation.
    J Antibiot (Tokyo). 2009 Apr;62(4):221-4.

  • Fukuda I, Ito A, Hirai G, Nishimura S, Kawasaki H, Saitoh H, Kimura K, Sodeoka M, Yoshida M.
    Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate.
    Chem Biol. 2009 Feb 27;16(2):133-40.

  • Ueoka R, Ito A, Izumikawa M, Maeda S, Takagi M, Shin-Ya K, Yoshida M, van Soest RW, Matsunaga S.
    Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin.
    Toxicon. 2009 May;53(6):680-4.

  • Zhou J, Vos CC, Gjyrezi A, Yoshida M, Khuri FR, Tamanoi F, Giannakakou P.
    The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner.
    J Biol Chem. 2009 Apr 10;284(15):9648-55.

  • Ling F, Yoshida M, Shibata T.
    Heteroduplex joint formation free of net topological change by Mhr1, a mitochondrial recombinase.
    J Biol Chem. 2009 Apr 3;284(14):9341-53.

  • Hori A, Yoshida M, Shibata T, Ling F.
    Reactive oxygen species regulate DNA copy number in isolated yeast mitochondria by triggering recombination-mediated replication.
    Nucleic Acids Res. 2009 Feb;37(3):749-61.

  • Matsuyama, A. and Yoshida, M.
    Systematic cloning of an ORFeome using the Gateway system.
    Methods Mol. Biol. 2009;577:11-24.

2008

  • Dohi Y, Ikura T, Hoshikawa Y, Katoh Y, Ota K, Nakanome A, Muto A, Omura S, Ohta T, Ito A, Yoshida M, Noda T, Igarashi K.
    Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.
    Nat Struct Mol Biol. 2008 Dec;15(12):1246-54.

  • Nishino TG, Miyazaki M, Hoshino H, Miwa Y, Horinouchi S, Yoshida M.
    14-3-3 regulates the nuclear import of class IIa histone deacetylases.
    Biochem Biophys Res Commun. 2008 Dec 19;377(3):852-6.

  • Hoshino I, Matsubara H, Komatsu A, Akutsu Y, Nishimori T, Yoneyama Y, Murakami K, Sakata H, Matsushita K, Miyazawa Y, Brooks R, Yoshida M, Ochiai T.
    Combined effects of p53 gene therapy and leptomycin B in human esophageal squamous cell carcinoma.
    Oncology. 2008 75(1-2):113-9.

  • Tokai T, Takahashi-Ando N, Izawa M, Kamakura T, Yoshida M, Fujimura M, Kimura M.
    4-O-acetylation and 3-O-acetylation of trichothecenes by trichothecene 15-O-acetyltransferase encoded by Fusarium Tri3.
    Biosci Biotechnol Biochem. 2008 Sep;72(9):2485-9.

  • Matsuyama A, Shirai A, Yoshida M.
    A novel series of vectors for chromosomal integration in fission yeast.
    Biochem Biophys Res Commun. 2008 Sep 19;374(2):315-9.

  • Crabb SJ, Howell M, Rogers H, Ishfaq M, Yurek-George A, Carey K, Pickering BM, East P, Mitter R, Maeda S, Johnson PW, Townsend P, Shin-ya K, Yoshida M, Ganesan A, Packham G.
    Characterisation of the in vitro activity of the depsipeptide histone deacetylase inhibitor spiruchostatin A.
    Biochem. Pharmacol. 2008 Aug 15;76(4):463-75.

  • Kamemura K, Ito A, Shimazu T, Matsuyama A, Maeda S, Yao TP, Horinouchi S, Khochbin S, Yoshida M.
    Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells.
    Biochem Biophys Res Commun. 2008 Sep 12;374(1):84-9.

  • Matsuyama A, Shirai A, Yoshida M.
    A series of promoters for constitutive expression of heterologous genes in fission yeast.
    Yeast. 2008 May;25(5):371-6.

  • Yoshitani A, Ling F, Yoshida M.
    The yeast checkpoint kinase Dun1 downregulates DIN7 in the absence of DNA damage.
    Biosci Biotechnol Biochem. 2008 Jun;72(6):1630-4.

  • Nakao Y, Narazaki G, Hoshino T, Maeda S, Yoshida M, Maejima H, Yamashita JK.
    Evaluation of antiangiogenic activity of azumamides by the in vitro vascular organization model using mouse induced pluripotent stem (iPS) cells.
    Bioorg Med Chem Lett. 2008 May 1;18(9):2982-4.

  • Kimata Y, Matsuyama A, Nagao K, Furuya K, Obuse C, Yoshida M, Yanagida M.
    Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin.
    J Cell Sci. 2008 Apr 1;121(Pt 7):1107-18.

  • Shirai A, Matsuyama A, Yashiroda Y, Hashimoto A, Kawamura Y, Arai R, Komatsu Y, Horinouchi S, Yoshida M.
    Global analysis of gel mobility of proteins and its use in target identification.
    J Biol Chem. 2008 Apr 18;283(16):10745-52. Epub 2008 Feb 21.

  • Yashiroda Y, Matsuyama A, Yoshida M.
    New insights into chemical biology from ORFeome libraries.
    Curr Opin Chem Biol. 2008 Feb;12(1): 55-9. Review.

  • Takahashi-Ando N, Ochiai N, Tokai T, Ohsato S, Nishiuchi T, Yoshida M, Fujimura M, Kimura M.
    A screening system for inhibitors of trichothecene biosynthesis: hydroxylation of trichodiene as a target.
    Biotechnol Lett. 2008 Jun;30(6):1055-9.

  • Matthias P, Yoshida M, Khochbin S.
    HDAC6 a new cellular stress surveillance factor.
    Cell Cycle. 2008 Jan;7(1):7-10.

  • Yoshitani A, Yoshida M, Ling F.
    A novel cis-acting element required for DNA damage-inducible expression of yeast DIN7.
    Biochem Biophys Res Commun. 2008 Jan 1;16(1):437-45.

  • Nishino N, Shivashimpi GM, Soni PB, Bhuiyan MP, Kato T, Maeda S, Nishino TG, Yoshida M.
    Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides.
    Bioorg Med Chem. 2008 Jan 4;365(1): 183-8.

2007

  • Lo CW, Kaida D, Nishimura S, Matsuyama A, Yashiroda Y, Taoka H, Ishigami K, Watanabe H, Nakajima H, Tani T, Horinouchi S, Yoshida M.
    Inhibition of splicing and nuclear retention of pre-mRNA by spliceostatin A in fission yeast.
    Biochem Biophys Res Commun. 2007 Dec 21;364(3): 573-7.

  • Yurek-George A, Cecil AR, Mo AH, Wen S, Rogers H, Habens F, Maeda S, Yoshida M, Packham G, Ganesan A.
    The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor.
    J Med Chem. Nov 15;50(23):5720-6. Epub 2007 Oct 24.

  • Shivashimpi GM, Amagai S, Kato T, Nishino N, Maeda S, Nishino TG, Yoshida M.
    Molecular design of histone deacetylase inhibitors by aromatic ring shifting in chlamydocin framework.
    Bioorg Med Chem. 2007 Dec 15;15(24):7830-9. Epub 2007 Aug 26.

  • Kaida D, Motoyoshi H, Tashiro E, Nojima T, Hagiwara M, Ishigami K, Watanabe H, Kitahara T, Yoshida T, Nakajima H, Tani T, Horinouchi S, Yoshida M.
    Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.
    Nat Chem Biol. 2007 Sep;3(9):576-83. Epub 2007 Jul 22.

  • Lee S, Shinji C, Ogura K, Shimizu M, Maeda S, Sato M, Yoshida M, Hashimoto Y, Miyachi H.
    Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.
    Bioorg Med Chem Lett. 2007 Sep 1;17(17):4895-900. Epub 2007 Jun 13.

  • Ling F, Hori A, Yoshida M, Shibata T.
    Rolling circle replication: a universal model for controlling mechanisms of mitochondrial DNA copy number.
    Tanpakushitsu Kakusan Koso. 2007 Jul;52(8):886-92. Review. Japanese.

  • Hoshino H, Nishino TG, Tashiro S, Miyazaki M, Ohmiya Y, Igarashi K, Horinouchi S, Yoshida M.
    Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression.
    J Biochem (Tokyo). 2007 May;141(5):719-27. Epub 2007 Mar 23.

  • Shimazu T, Horinouchi S, Yoshida M.
    Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing.
    J Biol Chem. 2007 Feb 16;282(7):4470-8. Epub 2006 Dec 17.

  • Tsuchiya A, Tashiro E, Yoshida M, Imoto M.
    Involvement of protein phosphatase 2A nuclear accumulation and subsequent inactivation of activator protein-1 in leptomycin B-inhibited cyclin D1 expression.
    Oncogene. 2007 Mar 8;26(11):1522-32. Epub 2006 Sep 11.

2006

  • Jang BC, Sung SH, Park JG, Park JW, Suh MH, Choi IH, Yoshida M, Yoo SK, Suh SI.
    Leptomycin B, a metabolite of Streptomyces, inhibits the expression of inducible nitric oxide synthase in BV2 microglial cells.
    Int J Oncol. 2006 Dec;29(6):1509-15.

  • Inoue K, Kobayashi M, Yano K, Miura M, Izumi A, Mataki C, Doi T, Hamakubo T, Reid PC, Hume DA, Yoshida M, Aird WC, Kodama T, Minami T.
    Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression.
    Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2652-9. Epub 2006 Sep 28.

  • Sasaki K, Yoshida M.
    Histone modification enzymes.
    Tanpakushitsu Kakusan Koso, 2006 Nov;51(14 Suppl):2069-75. Review. Japanese.

  • Suzuki T, Kouketsu A, Itoh Y, Hisakawa S, Maeda S, Yoshida M, Nakagawa H, Miyata N.
    Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate.
    J Med Chem. 2006 Aug 10;49(16):4809-12.

  • Shinji C, Maeda S, Imai K, Yoshida M, Hashimoto Y, Miyachi H.
    Design, synthesis, and evaluation of cyclic amide/imide-bearing hydroxamic acid derivatives as class-selective histone deacetylase (HDAC) inhibitors.
    Bioorg Med Chem. 2006 Nov 15;14(22):7625-51. Epub 2006 Jul 31.

  • Matsuyama A, Arai R, Yashiroda Y, Shirai A, Kamata A, Sekido S, Kobayashi Y, Hashimoto A, Hamamoto M, Hiraoka Y, Horinouchi S, Yoshida M.
    ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
    Nat. Biotechnol. 2006 Jul;24(7):841-7. Epub 2006 Jun 25.

  • Shimazu T, Komatsu Y, Nakayama KI, Fukazawa H, Horinouchi S, Yoshida M.
    Regulation of SV40 large T antigen stability by reversible acetylation.
    Oncogene. 2006 Nov 30;25(56):7391-400. Epub 2006 Jun 12.

  • Tomono A, Mashiko M, Shimazu T, Inoue H, Nagasawa H, Yoshida M, Ohnishi Y, Horinouchi S.
    Self-activation of serine/threonine kinase AfsK on autophosphorylation at threonine-168.
    J Antibiot (Tokyo). 2006 Feb;59(2):117-23.

  • Kataoka M, Hashimoto KI, Yoshida M, Nakamatsu T, Horinouchi S, Kawasaki H.
    Gene expression of Corynebacterium glutamicum in response to the conditions inducing glutamate overproduction.
    Lett Appl Microbiol. 2006 May;42(5):471-6.

  • Jeon EJ, Lee KY, Choi NS, Lee MH, Kim HN, Jin YH, Ryoo HM, Choi JY, Yoshida M, Nishino N, Oh BC, Lee KS, Lee YH, Bae SC.
    Bone morphogenetic protein-2 stimulates Runx2 acetylation.
    J Biol Chem. 2006 Jun 16;281(24):16502-11. Epub 2006 Apr 13.

  • Masumi A, Fukazawa H, Shimazu T, Yoshida M, Ozato K, Komuro K, Yamaguchi K.
    Nucleolin is involved in interferon regulatory factor-2-dependent transcriptional activation.
    Oncogene. 2006 Aug 24;25(37):5113-24. Epub 2006 Apr 3.

  • Tokunaga K, Shibuya T, Ishihama Y, Tadakuma H, Ide M, Yoshida M, Funatsu T, Ohshima Y, Tani T.
    Nucleocytoplasmic transport of fluorescent mRNA in living mammalian cells: nuclear mRNA export is coupled to ongoing gene transcription.
    Genes Cells. 2006 Mar;11(3):305-17.

  • Margolis SS, Perry JA, Weitzel DH, Freel CD, Yoshida M, Haystead TA, Kornbluth S.
    A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25.
    Mol Biol Cell. 2006 Apr;17(4):1779-89. Epub 2006 Feb 8.

  • Bhuiyan MP, Kato T, Okauchi T, Nishino N, Maeda S, Nishino TG, Yoshida M.
    Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases.
    Bioorg Med Chem. 2006 May 15;14(10):3438-46. Epub 2006 Jan 24.

  • Lee KH, Nishimura S, Matsunaga S, Fusetani N, Ichijo H, Horinouchi S, Yoshida M.
    Induction of a ribotoxic stress response that stimulates stress-activated protein kinases by 13-deoxytedanolide, an antitumor marine macrolide.
    Biosci Biotechnol Biochem. 2006 Jan;70(1): 161-71.

  • Hirokawa Y, Nheu T, Grimm K, Mautner V, Maeda S, Yoshida M, Komiyama K, Maruta H.
    Sichuan pepper extracts block the PAK1/cyclin D1 pathway and the growth of NF1-deficient cancer xenograft in mice.
    Cancer Biol Ther. 2006 Mar;5(3):305-9. Epub 2006 Mar 12.

  • Cheng Q, Balzer E, Miller S M, Yoshida M, and Wong J C
    Effect of histone deacetylase inhibitors on tubulin acetylation and development in Volvox carteri (Volvocales).
    J. Phycol. 2006 42: 417-422

  • Shirai A, Matsuyama A, Yashiroda Y, Arai R, and Yoshida M.
    Rapid and reliable preparation of total cell lysates from fission yeast.
    Nat. Protocols. DOI: 10.1038/nprot.2006.191.:, 2006.

2005

  • Tsuchiya A, Tashiro E, Yoshida M, Imoto M.
    Involvement of nuclear accumulation of heat shock protein 27 in leptomycin B-induced apoptosis in HeLa cells.
    J Antibiot (Tokyo). 2005 Dec;58(12):810-6.

  • Barnfield PC, Zhang X, Thanabalasingham V, Yoshida M, Hui CC.
    Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms.
    Differentiation. 2005 Oct;73(8):397-405.

  • Iwabata H, Yoshida M, Komatsu Y.
    Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies.
    Proteomics. 2005 Dec;5(18):4653-64.

  • Shinji C, Nakamura T, Maeda S, Yoshida M, Hashimoto Y, Miyachi H.
    Design and synthesis of phthalimide-type histone deacetylase inhibitors.
    Bioorg Med Chem Lett. 2005 Oct 15;15(20):4427-31.

  • Col E, Caron C, Chable-Bessia C, Legube G, Gazzeri S, Komatsu Y, Yoshida M, Benkirane M, Trouche D, Khochbin S.
    HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses.
    EMBO J. 2005 Jul 20;24(14):2634-45. Epub 2005 Jul 7.

  • Lee KH, Nishimura S, Matsunaga S, Fusetani N, Horinouchi S, Yoshida M.
    Inhibition of protein synthesis and activation of stress-activated protein kinases by onnamide A and theopederin B, antitumor marine natural products.
    Cancer Sci. 2005 Jun;96(6):357-64.

  • Kovacs JJ, Murphy PJM, Gaillard S, Zhao X, Wu JT, Nicchitta CV, Yoshida M, Toft DO, Pratt WB, Yao TP.
    HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of clucocorticoid receptor.
    Mol Cell. 2005 May 27;18(5):601-7.

  • Tatematsu K, Yoshimoto N, Koyanagi T, Tokunaga C, Tachibana T, Yoneda Y, Yoshida M, Okajima T, Tanizawa K, Kuroda S.
    Nuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its functional interaction with nuclear body proteins.
    J Biol Chem. 2005 Jun 17;280(24):22937-44. Epub 2005 Apr 15.

  • Saji S, Kawakami M, Hayashi S, Yoshida N, Hirose M, Horiguchi S, Itoh A, Funata N, Schreiber SL, Yoshida M, Toi M.
    Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer.
    Oncogene. 2005 Jun 30;24(28):4531-9.

  • Nishimura S, Matsunaga S, Yoshida M, Hirota H, Yokoyama S, Fusetani N.
    13-Deoxytedanolide, a marine sponge-derived antitumor macrolide, binds to the 60S large ribosomal subunit.
    Bioorg Med Chem. 2005 Jan 17;13(2):449-54.

2004

  • Matsuyama A, Shirai A, Yashiroda Y, Kamata A, Horinouchi S, Yoshida M.
    pDUAL, a multipurpose, multicopy vector capable of chromosomal integration in fission yeast.
    Yeast. 2004 Nov;21(15):1289-305.

  • Kamura T, Hara T, Matsumoto M, Ishida N, Okumura F, Hatakeyama S, Yoshida M, Nakayama K, Nakayama KI.
    Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase.
    Nat Cell Biol. 2004 Dec;6(12):1229-35. Epub 2004 Nov 7.

  • Motoyoshi H, Horigome M, Ishigami K, Yoshida T, Horinouchi S, Yoshida M, Watanabe H, Kitahara T.
    Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes.
    Biosci Biotechnol Biochem. 2004 Oct;68(10):2178-82.

  • Nishino N, Jose B, Shinta R, Kato T, Komatsu Y, Yoshida M.
    Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes.
    Bioorg Med Chem. 2004 Nov 15;12(22):5777-84.

  • Heltweg B, Dequiedt F, Marshall BL, Brauch C, Yoshida M, Nishino N, Verdin E, Jung M.
    Subtype selective substrates for histone deacetylases.
    J Med Chem. 2004 Oct 7;47(21):5235-43.

  • Jose B, Oniki Y, Kato T, Nishino N, Sumida Y, Yoshida M.
    Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones.
    Bioorg. Med. Chem. Lett. 2004 Nov 1;14(21):5343-6.

  • Jang BC, Paik JH, Jeong HY, Oh HJ, Park JW, Kwon TK, Song DK, Park JG, Kim SP, Bae JH, Mun KC, Suh MH, Yoshida M, Suh SI.
    Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells.
    Biochem Pharmacol. 2004 Jul 15;68(2):263-74.

  • Suzuki H, Tashiro S, Hira S, Sun J, Yamazaki C, Zenke Y, Ikeda-Saito M, Yoshida M, Igarashi K.
    Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1.
    EMBO J. 2004 Jul 7;23(13):2544-53. Epub 2004 Jun 3.

  • Yoshida M, Sazer S.
    Nucleocytoplasmic transport and nuclear envelope integrity in the fission yeast Schizosaccharomyces pombe.
    Methods, 2004 Jul;33(3):226-38.

  • Nishino N, Yoshikawa D, Watanabe LA, Kato T, Jose B, Komatsu Y, Sumida Y, Yoshida M.
    Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand.
    Bioorg. Med. Chem. Lett. 2004 May 17;14(10):2427-31.

  • Tashiro S, Muto A, Tanimoto K, Tsuchiya H, Suzuki H, Hoshino H, Yoshida M, Walter J, Igarashi K.
    Repression of PML nuclear body-associated transcription by oxidative stress-activated Bach2.
    Mol Cell Biol. 2004 Apr;24(8):3473-84.

  • Jose B, Okamura S, Kato T, Nishino N, Sumida Y, Yoshida M.
    Toward an HDAC6 inhibitor: synthesis and conformational analysis of cyclic hexapeptide hydroxamic acid designed from alpha-tubulin sequence.
    Bioorg. Med. Chem. 2004 Mar 15;12(6):1351-6.

  • Uchida S, Ohtsubo M, Shimura M, Hirata M, Nakagama H, Matsunaga T, Yoshida M, Ishizaka Y, Yamashita K.
    Nuclear export signal in CDC25B.
    Biochem Biophys Res Commun. 2004 Mar 26;316(1):226-32.

  • Watanabe LA, Jose B, Kato T, Nishino N, and Yoshida M.
    Synthesis of L-a-amino-w-bromoalkanoic acid for side chain modification.
    Tetrahedron Lett. 45: 491-494, 2004.
Copyright(c) 2018 Chemical Genetics Laboratory, RIKEN. All Rights Reserved.