Current Members
Research Scientist
KUROSAWA, Gen
g.kurosawa[at]riken.jp
- Theme:
- Mathematical Biology, Chronobiology, Biophysics
- Contents:
- My research interest is about evolution of biological systems such as molecular networks. One of our study was the modeling of difference of circadian period between species. Currently, I have been studying stability of circadian rhythms as well as preciseness of differentiation processes.
Education
- 2000.3
- B.S. - Kyushu University, Fukuoka, Japan
- 2000.4
- Master Course, Kyushu University
- 2002.3
- M.S. - Kyushu University
- 2005.3
- Ph.D. - Kyushu University
TOP
Positions
- 2003.4 - 2005.3
- Research Fellow of JSPS
- 2005.4 - 2008.3
- Postdoctoral Resercher, ERATO Aihara Complexity Modelling Project, JST
- 2008.4 - 2009.3
- Postdoctoral Fellow of JSPS
- 2009.4 - Present
- Reserch Scientist, Theoretical Biology Laboratory, RIKEN
TOP
Publications
- Fiedler, B., Mochizuki, A., Kurosawa, G., and Saito, D., (2013) Dynamics and control at feedback vertex sets I. Informative and determining nodes in regulatory networks. J. Dyn. Differ. Eqns. (In Press) doi: 10.1007/s10884-013-9312-7
- Mochizuki, A., Fiedler, B., Kurosawa, G., and Saito, D., (2013) Dynamics and control at feedback vertex sets. II: A faithful monitor to determine the diversity of molecular activities in regulatory networks. J. Theor. Biol. (In Press) doi: 10.1016/j.jtbi.2013.06.009
- Takasu, N.N., Kurosawa, G., Tokuda, I.T., Mochizuki, A., Todo, T., and Nakamura, W., (2012) Circadian regulation of food-anticipatory activity in molecular clock-deficient mice. PLoS ONE. 7(11): e48892. doi: doi: 10.1371/journal.pone.0048892
- Tsumoto, K., Kurosawa, G., Yoshinaga, T., and Aihara, K., (2011) Modeling light adaptation in circadian clock: prediction of the response that stabilizes entrainment. PLoS ONE. 6(6): e20880. doi: 10.1371/journal.pone.0020880
- Ogawa, Y., Koike, N., Kurosawa, G., Soga, T., Tomita, M., and Tei, H., (2011) Positive feedback regulation generates the expression phase difference between mammalian clock genes Per2. PLoS ONE. 6(4): e18663. doi: 10.1371/journal.pone.0018663
- Takeuchi, T., Hinohara, T., Kurosawa, G., and Uchida, K., (2007) A temperature-compensated model for circadian rhythms that can be entrained by temperature cycles. J. Theor. Biol. 246: 195-204. doi: 10.1016/j.jtbi.2006.12.028
- Kurosawa, G., Aihara, K., and Iwasa, Y., (2006) A model for the circadian rhythm of cyanobacteria that maintains oscillation without gene expression. Biophys. J. 91: 2015 - 23. doi: 10.1529/biophysj.105.076554
- Kurosawa, G., and Goldbeter, A., (2006) Amplitude of circadian oscillations entrained by 24-h light-dark cycles. J. Theor. Biol. 242: 478 - 88. doi: 10.1016/j.jtbi.2006.03.016
- Kurosawa, G., and Iwasa, Y., (2005) Temperature compensation in circadian clock models. J. Theor. Biol. 233: 453-68. doi: 10.1016/j.jtbi.2004.10.012
- Kurosawa, G., and Iwasa, Y., (2002) Saturation of enzyme kinetics in circadian clock models. J. Biol. Rhythms 17: 568-577. doi: 10.1177/0748730402238239
- Kurosawa, G., Mochizuki, A., and Iwasa, Y., (2002) Processes promoting oscillations -- comparative study of circadian clock models. J. Theor. Biol. 216: 193-208. doi: 10.1006/jtbi.2002.2546