Research Scientist

KUROSAWA, Gen g.kurosawa[at]riken.jp

Theme：

Mathematical Biology, Chronobiology, Biophysics

Contents：

My research interest is about evolution of biological systems such as molecular networks. One of our study was the modeling of difference of circadian period between species. Currently, I have been studying stability of circadian rhythms as well as preciseness of differentiation processes.

2000.3

B.S. - Kyushu University, Fukuoka, Japan

2000.4

Master Course, Kyushu University

2002.3

M.S. - Kyushu University

2005.3

Ph.D. - Kyushu University

2003.4 - 2005.3

Research Fellow of JSPS

2005.4 - 2008.3

Postdoctoral Resercher, ERATO Aihara Complexity Modelling Project, JST

2008.4 - 2009.3

Postdoctoral Fellow of JSPS

2009.4 - Present

Reserch Scientist, Theoretical Biology Laboratory, RIKEN

• Fiedler, B., Mochizuki, A., Kurosawa, G., and Saito, D., (2013) Dynamics and control at feedback vertex sets I. Informative and determining nodes in regulatory networks. J. Dyn. Differ. Eqns. (In Press) doi: 10.1007/s10884-013-9312-7
• Mochizuki, A., Fiedler, B., Kurosawa, G., and Saito, D., (2013) Dynamics and control at feedback vertex sets. II: A faithful monitor to determine the diversity of molecular activities in regulatory networks. J. Theor. Biol. (In Press) doi: 10.1016/j.jtbi.2013.06.009
• Takasu, N.N., Kurosawa, G., Tokuda, I.T., Mochizuki, A., Todo, T., and Nakamura, W., (2012) Circadian regulation of food-anticipatory activity in molecular clock-deficient mice. PLoS ONE. 7(11): e48892. doi: doi: 10.1371/journal.pone.0048892
• Tsumoto, K., Kurosawa, G., Yoshinaga, T., and Aihara, K., (2011) Modeling light adaptation in circadian clock: prediction of the response that stabilizes entrainment. PLoS ONE. 6(6): e20880. doi: 10.1371/journal.pone.0020880
• Ogawa, Y., Koike, N., Kurosawa, G., Soga, T., Tomita, M., and Tei, H., (2011) Positive feedback regulation generates the expression phase difference between mammalian clock genes Per2. PLoS ONE. 6(4): e18663. doi: 10.1371/journal.pone.0018663
• Takeuchi, T., Hinohara, T., Kurosawa, G., and Uchida, K., (2007) A temperature-compensated model for circadian rhythms that can be entrained by temperature cycles. J. Theor. Biol. 246: 195-204. doi: 10.1016/j.jtbi.2006.12.028
• Kurosawa, G., Aihara, K., and Iwasa, Y., (2006) A model for the circadian rhythm of cyanobacteria that maintains oscillation without gene expression. Biophys. J. 91: 2015 - 23. doi: 10.1529/biophysj.105.076554
• Kurosawa, G., and Goldbeter, A., (2006) Amplitude of circadian oscillations entrained by 24-h light-dark cycles. J. Theor. Biol. 242: 478 - 88. doi: 10.1016/j.jtbi.2006.03.016
• Kurosawa, G., and Iwasa, Y., (2005) Temperature compensation in circadian clock models. J. Theor. Biol. 233: 453-68. doi: 10.1016/j.jtbi.2004.10.012
• Kurosawa, G., and Iwasa, Y., (2002) Saturation of enzyme kinetics in circadian clock models. J. Biol. Rhythms 17: 568-577. doi: 10.1177/0748730402238239
• Kurosawa, G., Mochizuki, A., and Iwasa, Y., (2002) Processes promoting oscillations -- comparative study of circadian clock models. J. Theor. Biol. 216: 193-208. doi: 10.1006/jtbi.2002.2546