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Publications 1986-1999


  • Kimura, K., V. V. Rybenkov, N. J. Crisona, T. Hirano* and N. R. Cozzarelli*. (1999). 13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation. Cell. 98:239-248 (*co-corresponding authors).
    PMID: 10428035
  • Hirano, T. (1999). SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates? Genes Dev. 13:11-19.
    PMID: 9887095

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  • Hirano, M. and T. Hirano. (1998). ATP-dependent aggregation of single-stranded DNA by a bacterial SMC homodimer. EMBO J. 17:7139-7148.
    PMID: 9843517
  • Kimura, K., M. Hirano, R. Kobayashi and T. Hirano. (1998). Phosphorylation and activation of 13S condensin by cdc2 in vitro. Science. 282:487-490.
    PMID: 9774278
  • Losada, A., M. Hirano and T. Hirano. (1998). Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev. 12:1986-1997.
    PMID: 9649503
  • Hirano, T. (1998). SMC protein complexes and higher-order chromosome dynamics. Curr Opin Cell Biol. 10:317-322.
    PMID: 9640531

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  • Kimura, K. and T. Hirano. (1997). ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation. Cell. 90:625-634.
    PMID: 9288743
  • Hirano, T., R. Kobayashi and M. Hirano. (1997). Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein. Cell. 89:511-521.
    PMID: 9160743

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  • Swedlow, J. R. and T. Hirano. (1996). Chromosome dynamics: fuzzy sequences, specific attachment? Curr Biol. 6:544-547.
    PMID: 8805264
  • Hirano, T. (1995). Biochemical and genetic dissection of mitotic chromosome condensation. Trends Biochem Sci. 20: 357-361.
    PMID: 7482703
  • Hirano, T., T. J. Mitchison and J. R. Swedlow. (1995). The SMC family: from chromosome condensation to dosage compensation. Curr Opin Cell Biol. 7:329-336.
    PMID: 7662362
  • Vernos, I., J. Raats, T. Hirano, J. Heasman, E. Karsenti and C. Wylie. (1995). Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. Cell. 81:117-127.
    PMID: 7720067
  • Hirano, T. and T. J. Mitchison. (1994). A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro. Cell. 79:449-458.
    PMID: 7954811
  • Hirano, T. and T. J. Mitchison. (1993). Topoisomerase II does not play a scaffolding role in the organization of mitotic chromosomes assembled in Xenopus egg extracts. J Cell Biol. 120:601-612.
    PMID: 8381118
  • Hirano, T. and T. J. Mitchison. (1991). Cell cycle control of higher-order chromatin assembly around naked DNA in vitro. J Cell Biol. 115:1479-1489.
    PMID: 1661728

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  • Uzawa., S., I. Samejima, T. Hirano, K. Tanaka and M. Yanagida. (1990). The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene. Cell. 62:913-925.
    PMID: 2203537
  • Masuda, H., T. Hirano, M. Yanagida and W. Z. Cande. (1990). In Vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells. J Cell Biol. 110:417-425.
    PMID: 2404993
  • Hirano, T., N. Kinoshita, K. Morikawa and M. Yanagida. (1990). Snap helix with knob and hole: essential repeats in S. pombe nuclear protein nuc2+. Cell. 60:319-328.
    PMID: 2297790
  • Hirano, T., G. Konoha, T. Toda and M. Yanagida. (1989). Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus. J Cell Biol. 108:243-253.
    PMID: 2537310
  • Hirano, T. and M. Yanagida. (1989). Controlling elements in the cell division cycle of Schizosaccharomyces pombe. In Molecular and Cell Biology of Yeasts. E. F. Waltan, ed. Blackie and son Ltd., Glasgow. pp223-245.
  • Hirano, T., Y. Hiraoka and M. Yanagida. (1988). A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase. J Cell Biol. 106:1171-1183.
    PMID: 3283148
  • Yanagida, M., Y. Hiraoka, T. Uemura, S. Miyake and T. Hirano. (1986). Control mechanism of chromosome movement in mitosis of fission yeast. In Yeast Cell Biology. UCLA Symposia on Molecular and Cellular Biology. Vol.33. J. Hicks, ed. Alan R. Liss Inc., New York. pp279-297.
  • Hirano, T., S. Funahashi, T. Uemura and M. Yanagida. (1986). Isolation and characterization of Schizosaccharomyces pombe cut mutants that block nuclear division but not cytokinesis. EMBO J. 5:2973-2979.
    PMID: 16453724

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Chromosome Dynamics Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan
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