Katsuhiko Kamada, Ph. D.

Education

1993-96	School of Science, Department of Genetics, The Graduate University for Advanced Studies, (National Institute of Genetics in Mishima) Japan. Awarded the degree of Ph. D.

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Research and Professional Experience

1993-96	Visiting Researcher, Protein Engineering Research Institute /Biomolecular Engineering Research Institute, Japan.
1996-97	Postdoctoral Associate, Biomolecular Engineering Research Institute, Japan.
1997-2001	Postdoctoral Fellow of HFSP / Postdoctoral Associate of HHMI, Laboratories of Biophysics, Rockefeller University, U.S.A.
2002-06	Researcher Scientist / Senior Research Scientist, Cellular Physiology Laboratory, RIKEN, Japan.
2006-present	Senior Research Scientist, Chromosome Dynamics Laboratory, RIKEN, Japan.

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Publication List

• Kamada, K. and D. Barilla. (2018). Combing chromosomal DNA mediated by the SMC complex: structure and mechanisms. Bioessays. 40: doi: 10.1002/bies.201700166.
  PMID: 29226983
• Kamada, K., M. Su'etsugu, H. Takada, M. Miyata and T. Hirano. (2017). Overall shapes of the SMC-ScpAB complex are determined by balance between constraint and relaxation of its structural parts. Structure. 25:603-616.
  PMID: 28286005
• Feng, S., Y. Chen, K. Kamada, H. Wang, K. Tang, M. Wang and Y. G. Gao. (2013). YoeB-ribosome structure: a canonical RNase that requires the ribosome for its specific activity. Nucleic Acids Res. 41:9549-56.
  PMID: 23945936
• You, Z., M. De Falco, K. Kamada, F. M. Pisani and H. Masai. (2013). The mini-chromosome maintenance (Mcm) complexes interact with DNA polymerase α-primase and stimulate its ability to synthesize RNA primers. PLoS One. 8:e72408.
  PMID: 23977294
• Kamada, K., M. Miyata and T. Hirano. (2013). Molecular basis of SMC ATPase activation: role of internal structural changes of the regulatory subcomplex ScpAB. Structure. 21:581-594.
  PMID: 23541893
• Kamada, K. (2012). The GINS complex: structure and function. Subcell Biochem. 62:135-156.
  PMID: 22918584
• Jee, J., T. Mizuno, K. Kamada, H. Tochio, Y. Chiba, K. I. Yanagi, G. Yasuda, H. Hiroaki, F. Hanaoka and M. Shirakawa. (2010). Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable to identify the key residues for binding to replicative helicase Mcm proteins. J Biol Chem. 285:15931-15940.
  PMID: 20335175
• Kamada, K., Y. Kubota, T. Arata, Y. Shindo and F. Hanaoka. (2007). (as a corresponding author.) Structure of the human GINS complex and its assembly and functional interface in replication initiation. Nat Struct Mol Biol. 14:388-396.
  PMID: 17417653
• Kamada, K. and F. Hanaoka. (2005). (as a corresponding author.) Conformational change in the catalytic site of the ribonuclease YoeB toxin by YefM antitoxin. Mol Cell. 19:497-509.
  PMID: 16109374
• Kamada, K., F. Hanaoka and S. K. Burley. (2003). Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognition. Mol Cell. 11:875-884.
  PMID: 12718874
• Trester-Zedlitz, M., K. Kamada, S. K. Burley, D. Fenyö, B. T. Chait and T. W. Muir. (2003). A modular cross-linking approach for exploring protein interactions. J Am Chem Soc. 125:2416-2425.
  PMID: 12603129
• Kamada, K., R. G. Roeder and S. K. Burley. (2003). Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF. Proc Natl Acad Sci USA. 100:2296-2299.
  PMID: 12591941
• Burley, S. K. and K. Kamada. (2002). Transcription factor complexes. Curr Opin Struct Biol. 12:225-230.
  PMID: 11959501
• Kamada, K., F. Shu, H. Chen, S. Malik, G. Stelzer, R. G. Roeder, M. Meisterernst and S. K. Burley. (2001). Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. Cell. 106:71-81.
  PMID: 11461703
• Kamada, K., J. De Angelis, R. G. Roeder and S. K. Burley. (2001). Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF. Proc Natl Acad Sci USA. 98:3115-3120.
  PMID: 11248041
• Kamada, K., T. Horiuchi, K. Ohsumi, N. Shimamoto and K. Morikawa. (1996). Structure of a replication-terminator protein complexed with DNA. Nature. 383:598-603.
  PMID: 8857533
• Kamada, K., K. Ohsumi, T. Horiuchi, N. Shimamoto and K. Morikawa. (1996). Crystallization and preliminary X-ray analysis of the Escherichia coli replication terminator protein complexed with DNA. Proteins. 24:402-403.
  PMID: 8778788

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